1ih4: Difference between revisions
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
==Multi-Conformation Crystal Structure of GGm5CGCC== | ==Multi-Conformation Crystal Structure of GGm5CGCC== | ||
<StructureSection load='1ih4' size='340' side='right' caption='[[1ih4]], [[Resolution|resolution]] 1.90Å' scene=''> | <StructureSection load='1ih4' size='340' side='right' caption='[[1ih4]], [[Resolution|resolution]] 1.90Å' scene=''> | ||
| Line 5: | Line 6: | ||
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=5CM:5-METHYL-2-DEOXY-CYTIDINE-5-MONOPHOSPHATE'>5CM</scene></td></tr> | </td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=5CM:5-METHYL-2-DEOXY-CYTIDINE-5-MONOPHOSPHATE'>5CM</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ih1|1ih1]], [[1ih2|1ih2]], [[1ih3|1ih3]], [[1ih6|1ih6]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ih1|1ih1]], [[1ih2|1ih2]], [[1ih3|1ih3]], [[1ih6|1ih6]]</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ih4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ih4 OCA], [http://pdbe.org/1ih4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ih4 RCSB], [http://www.ebi.ac.uk/pdbsum/1ih4 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ih4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ih4 OCA], [http://pdbe.org/1ih4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ih4 RCSB], [http://www.ebi.ac.uk/pdbsum/1ih4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1ih4 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
Revision as of 13:44, 27 September 2017
Multi-Conformation Crystal Structure of GGm5CGCCMulti-Conformation Crystal Structure of GGm5CGCC
Structural highlights
Publication Abstract from PubMedThe transition between B- and A-DNA was first observed nearly 50 years ago. We have now mapped this transformation through a set of single-crystal structures of the sequence d(GGCGCC)2, with various intermediates being trapped by methylating or brominating the cytosine bases. The resulting pathway progresses through 13 conformational steps, with a composite structure that pairs A-nucleotides with complementary B-nucleotides serving as a distinct transition intermediate. The details of each step in the conversion of B- to A-DNA are thus revealed at the atomic level, placing intermediates for this and other sequences in the context of a common pathway. A crystallographic map of the transition from B-DNA to A-DNA.,Vargason JM, Henderson K, Ho PS Proc Natl Acad Sci U S A. 2001 Jun 19;98(13):7265-70. Epub 2001 Jun 5. PMID:11390969[1] From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. References
|
| ||||||||||||||||||