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==Crystal structure of the core fragment of MutY from E.coli at 1.2A resolution== | ==Crystal structure of the core fragment of MutY from E.coli at 1.2A resolution== | ||
<StructureSection load='1kg2' size='340' side='right' caption='[[1kg2]], [[Resolution|resolution]] 1.20Å' scene=''> | <StructureSection load='1kg2' size='340' side='right' caption='[[1kg2]], [[Resolution|resolution]] 1.20Å' scene=''> | ||
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1kg3|1kg3]], [[1kg4|1kg4]], [[1kg5|1kg5]], [[1kg6|1kg6]], [[1kg7|1kg7]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1kg3|1kg3]], [[1kg4|1kg4]], [[1kg5|1kg5]], [[1kg6|1kg6]], [[1kg7|1kg7]]</td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">mutY ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr> | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">mutY ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1kg2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kg2 OCA], [http://pdbe.org/1kg2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1kg2 RCSB], [http://www.ebi.ac.uk/pdbsum/1kg2 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1kg2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kg2 OCA], [http://pdbe.org/1kg2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1kg2 RCSB], [http://www.ebi.ac.uk/pdbsum/1kg2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1kg2 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
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<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1kg2 ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
*[[DNA glycosylase|DNA glycosylase]] | *[[DNA glycosylase|DNA glycosylase]] | ||
__TOC__ | __TOC__ | ||
Revision as of 10:20, 11 October 2017
Crystal structure of the core fragment of MutY from E.coli at 1.2A resolutionCrystal structure of the core fragment of MutY from E.coli at 1.2A resolution
Structural highlights
Function[MUTY_ECOLI] Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP). Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also |
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