3c6m: Difference between revisions
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|PDB= 3c6m |SIZE=350|CAPTION= <scene name='initialview01'>3c6m</scene>, resolution 2.45Å | |PDB= 3c6m |SIZE=350|CAPTION= <scene name='initialview01'>3c6m</scene>, resolution 2.45Å | ||
|SITE= <scene name='pdbsite=AC1:Spm+Binding+Site+For+Residue+A+501'>AC1</scene>, <scene name='pdbsite=AC2:Spm+Binding+Site+For+Residue+B+501'>AC2</scene>, <scene name='pdbsite=AC3:Spm+Binding+Site+For+Residue+C+501'>AC3</scene>, <scene name='pdbsite=AC4:Spm+Binding+Site+For+Residue+D+501'>AC4</scene>, <scene name='pdbsite=AC5:Mta+Binding+Site+For+Residue+A+401'>AC5</scene>, <scene name='pdbsite=AC6:Mta+Binding+Site+For+Residue+B+401'>AC6</scene>, <scene name='pdbsite=AC7:Mta+Binding+Site+For+Residue+C+401'>AC7</scene> and <scene name='pdbsite=AC8:Mta+Binding+Site+For+Residue+D+401'>AC8</scene> | |SITE= <scene name='pdbsite=AC1:Spm+Binding+Site+For+Residue+A+501'>AC1</scene>, <scene name='pdbsite=AC2:Spm+Binding+Site+For+Residue+B+501'>AC2</scene>, <scene name='pdbsite=AC3:Spm+Binding+Site+For+Residue+C+501'>AC3</scene>, <scene name='pdbsite=AC4:Spm+Binding+Site+For+Residue+D+501'>AC4</scene>, <scene name='pdbsite=AC5:Mta+Binding+Site+For+Residue+A+401'>AC5</scene>, <scene name='pdbsite=AC6:Mta+Binding+Site+For+Residue+B+401'>AC6</scene>, <scene name='pdbsite=AC7:Mta+Binding+Site+For+Residue+C+401'>AC7</scene> and <scene name='pdbsite=AC8:Mta+Binding+Site+For+Residue+D+401'>AC8</scene> | ||
|LIGAND= | |LIGAND= <scene name='pdbligand=MTA:5'-DEOXY-5'-METHYLTHIOADENOSINE'>MTA</scene>, <scene name='pdbligand=SPM:SPERMINE'>SPM</scene> | ||
|ACTIVITY= [http://en.wikipedia.org/wiki/Spermine_synthase Spermine synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.22 2.5.1.22] | |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Spermine_synthase Spermine synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.22 2.5.1.22] </span> | ||
|GENE= SMS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | |GENE= SMS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | ||
|DOMAIN= | |||
|RELATEDENTRY=[[3c6k|3C6K]] | |||
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3c6m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3c6m OCA], [http://www.ebi.ac.uk/pdbsum/3c6m PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=3c6m RCSB]</span> | |||
}} | }} | ||
'''Crystal structure of human spermine synthase in complex with spermine and 5-methylthioadenosine''' | '''Crystal structure of human spermine synthase in complex with spermine and 5-methylthioadenosine''' | ||
==Disease== | |||
Known disease associated with this structure: Mental retardation, X-linked, Snyder-Robinson type OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=300105 300105]], Smith-Magenis syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=607642 607642]] | |||
==About this Structure== | ==About this Structure== | ||
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[[Category: Wu, H.]] | [[Category: Wu, H.]] | ||
[[Category: Zeng, H.]] | [[Category: Zeng, H.]] | ||
[[Category: phosphoprotein]] | [[Category: phosphoprotein]] | ||
[[Category: sgc]] | [[Category: sgc]] | ||
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[[Category: structural genomics consortium]] | [[Category: structural genomics consortium]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 05:30:56 2008'' | ||