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==Structure and Binding Interface of the Cytosolic Tails of aXb2 Integrin== | ==Structure and Binding Interface of the Cytosolic Tails of aXb2 Integrin== | ||
<StructureSection load='2luv' size='340' side='right' caption='[[2luv]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | <StructureSection load='2luv' size='340' side='right' caption='[[2luv]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | ||
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<table><tr><td colspan='2'>[[2luv]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LUV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LUV FirstGlance]. <br> | <table><tr><td colspan='2'>[[2luv]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LUV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LUV FirstGlance]. <br> | ||
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2lke|2lke]], [[2lkj|2lkj]]</td></tr> | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2lke|2lke]], [[2lkj|2lkj]]</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2luv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2luv OCA], [http://pdbe.org/2luv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2luv RCSB], [http://www.ebi.ac.uk/pdbsum/2luv PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2luv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2luv OCA], [http://pdbe.org/2luv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2luv RCSB], [http://www.ebi.ac.uk/pdbsum/2luv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2luv ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == |
Revision as of 01:47, 10 August 2018
Structure and Binding Interface of the Cytosolic Tails of aXb2 IntegrinStructure and Binding Interface of the Cytosolic Tails of aXb2 Integrin
Structural highlights
Function[ITAX_HUMAN] Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis. See Also |
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