Inosine monophosphate dehydrogenase: Difference between revisions
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== Function == | == Function == | ||
'''Inosine monophosphate dehydrogenase''' (IMPDH) is part of the GTP biosynthesis and catalyzes the conversion of inosine monophosphate to xanthosine monophosphate while reducing NAD. IMPDH is inhibited by ribavirin and mycophenolic acid. | '''Inosine monophosphate dehydrogenase''' (IMPDH) is part of the GTP biosynthesis and catalyzes the conversion of inosine monophosphate to xanthosine monophosphate while reducing [[NAD]]. IMPDH is inhibited by ribavirin and mycophenolic acid<ref>PMID:8681386</ref>. | ||
== Disease == | == Disease == | ||
IMPDH level of activity is suggested to determine whether acute leukemia cells proliferate or differentiate<ref>PMID:2885446</ref>. | |||
== Structural highlights == | == Structural highlights == | ||