SCF-KIT: Difference between revisions
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== Introduction == | |||
'''Stem cell factor (SCF)''' is a cytokine that mediates its diverse cellular responses by binding to and activating the [https://en.wikipedia.org/wiki/Receptor_tyrosine_kinase receptor tyrosine kinase (RTK)] [https://en.wikipedia.org/wiki/CD117 KIT] (also known as SCF receptor). [https://en.wikipedia.org/wiki/Stem_cell_factor SCF] functions as a noncovalent homodimer, and both membrane-anchored and soluble forms of SCF have been described. | '''Stem cell factor (SCF)''' is a cytokine that mediates its diverse cellular responses by binding to and activating the [https://en.wikipedia.org/wiki/Receptor_tyrosine_kinase receptor tyrosine kinase (RTK)] [https://en.wikipedia.org/wiki/CD117 KIT] (also known as SCF receptor). [https://en.wikipedia.org/wiki/Stem_cell_factor SCF] functions as a noncovalent homodimer, and both membrane-anchored and soluble forms of SCF have been described. | ||
KIT was initially discovered as an oncogene in a feline retrovirus. | KIT was initially discovered as an oncogene in a feline retrovirus. | ||