Signalosome: Difference between revisions
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<StructureSection load='4d10' size='340' side='right' caption='Human COP9 signalosome subunits 1 (grey and wheat), 2 (green and blue), 3 (pink and rust), 4 (yellow and aqua), 5 (magenta and olive), 6 (cyan and orchid), 7A (gold and turquoise), 8 (red and neon green) (PDB code [[4d10]])' scene=''> | <StructureSection load='4d10' size='340' side='right' caption='Human COP9 signalosome subunits 1 (grey and wheat), 2 (green and blue), 3 (pink and rust), 4 (yellow and aqua), 5 (magenta and olive), 6 (cyan and orchid), 7A (gold and turquoise), 8 (red and neon green) (PDB code [[4d10]])' scene=''> | ||
'''COP9 (COnstitutive Photomorphogenesis 9) signalosome''' catalyzes the hydrolysis of NEDD8 protein from the cullin subunit of cullin-ring ubiquitin ligase. COP9 functions in the ubiquitin-proteasome pathway. COP9 contains 8 subunits and is homologous to the lid of the 26S proteasome. | '''COP9 (COnstitutive Photomorphogenesis 9) signalosome''' catalyzes the hydrolysis of NEDD8 protein from the cullin subunit of cullin-ring ubiquitin ligase. COP9 functions in the ubiquitin-proteasome pathway. COP9 contains 8 subunits and is homologous to the lid of the 26S proteasome<ref>PMID:16045761</ref>. | ||
</StructureSection> | </StructureSection> |