Beta2 adrenergic receptor-Gs protein complex: Difference between revisions
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== G-Protein variability == | == G-Protein variability == | ||
The Gαs subunit consists of two domains, the Ras domain (αRas) and the α-helical domain (αAH). Both are involved in nucleotide binding. A big discovery made thanks to this structure is that the Gα subunit has large variability between its GTP bound (active) and nucleotide free states, where the αAH domain has a <scene name='70/701430/Gamorph/2'>variable position</scene> relative to the αRas domain. | The Gαs subunit consists of two domains, the <scene name='70/701430/Alpharas/1'>Ras domain (αRas)</scene> and the <scene name='70/701430/Alphahelical/1'>α-helical domain (αAH)</scene>. Both are involved in nucleotide binding. A big discovery made thanks to this structure is that the Gα subunit has large variability between its GTP bound (active) and nucleotide free states, where the αAH domain has a <scene name='70/701430/Gamorph/2'>variable position</scene> relative to the αRas domain. | ||
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