3jag: Difference between revisions

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-'''Unreleased structure'''
+==Structure of a mammalian ribosomal termination complex with ABCE1, eRF1(AAQ), and the UAA stop codon==
+<StructureSection load='3jag' size='340' side='right' caption='[[3jag]], [[Resolution|resolution]] 3.65&Aring;' scene=''>
-The entry 3jag is ON HOLD
+== Structural highlights ==
+<table><tr><td colspan='2'>[[3jag]] is a 87 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JAG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3JAG FirstGlance]. <br>
-Authors: Brown, A., Shao, S., Murray, J., Hegde, R.S., Ramakrishnan, V.
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3jah|3jah]], [[3jai|3jai]]</td></tr>
-Description: Structure of a mammalian ribosomal termination complex with ABCE1, eRF1(AAQ), and the UAA stop codon
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3jag FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jag OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3jag RCSB], [http://www.ebi.ac.uk/pdbsum/3jag PDBsum]</span></td></tr>
-[[Category: Unreleased Structures]]
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/U3KPD5_RABIT U3KPD5_RABIT]] Binds to the 23S rRNA.[RuleBase:RU000576] [[http://www.uniprot.org/uniprot/ERF1_HUMAN ERF1_HUMAN]] Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.<ref>PMID:7990965</ref>  [[http://www.uniprot.org/uniprot/G1SS70_RABIT G1SS70_RABIT]] May play a role during erythropoiesis through regulation of transcription factor DDIT3.[HAMAP-Rule:MF_03122]
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Oryctolagus cuniculus]]
 [[Category: Brown, A]]
-[[Category: Shao, S]]
+[[Category: Hegde, R S]]
 [[Category: Murray, J]]
-[[Category: Hegde, R.S]]
 [[Category: Ramakrishnan, V]]
+[[Category: Shao, S]]
+[[Category: Abce1]]
+[[Category: Erf1]]
+[[Category: Ribosome]]
+[[Category: Termination]]