Isopenicillin N synthase: Difference between revisions
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Michal Harel (talk | contribs) No edit summary |
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{{STRUCTURE_1blz| PDB=1blz | SIZE=400| SCENE= |right|CAPTION=Isopenicilln N synthase complex with ACV and NO, [[1blz]] }} | {{STRUCTURE_1blz| PDB=1blz | SIZE=400| SCENE= |right|CAPTION=Isopenicilln N synthase complex with ACV and NO, [[1blz]] }} | ||
== Function == | |||
'''Isopenicillin N synthase''' (IPNS) is an iron-dependent enzyme which catalyzes the formation of isopenicillin N (IPN) from the tripeptide aminoadipoyl-cysteine-valine (ACV). IPNS participates in the biosynthesis of penicillin and cephalosporin antibiotics. The active site of IPNS contains an Fe atom. The reaction involves the reduction of O2 molecule to H2O<ref>PMID:9194566</ref>. | |||
== Structural highlights == | |||
==3D structures of isopenicillin N synthase== | ==3D structures of isopenicillin N synthase== | ||
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**[[1ips]] – AnIPNS | **[[1ips]] – AnIPNS | ||
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== References == | |||
<references/> | |||
[[Category: Topic Page]] | [[Category: Topic Page]] | ||