4y20: Difference between revisions
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==Complex of human Galectin-1 and NeuAcalpha2-3Galbeta1-4Glc== | |||
<StructureSection load='4y20' size='340' side='right' caption='[[4y20]], [[Resolution|resolution]] 2.20Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4y20]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y20 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Y20 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SLT:5-(ACETYLAMINO)-3,5-DIDEOXYNON-2-ULOPYRANONOSYL-(2- 3)-BETA-D-LYXO-HEXOPYRANOSYL-(1- 4)HEXOPYRANOSE'>SLT</scene></td></tr> | |||
[[ | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr> | ||
[[Category: Hsieh, T | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4y1v|4y1v]], [[4y1u|4y1u]], [[4y1x|4y1x]], [[4y1y|4y1y]], [[4y1z|4y1z]], [[4y22|4y22]], [[4y24|4y24]], [[4y26|4y26]]</td></tr> | ||
[[Category: Lin, H | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4y20 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y20 OCA], [http://pdbe.org/4y20 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4y20 RCSB], [http://www.ebi.ac.uk/pdbsum/4y20 PDBsum]</span></td></tr> | ||
[[Category: Lin, | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/LEG1_HUMAN LEG1_HUMAN]] May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase.<ref>PMID:14617626</ref> <ref>PMID:18796645</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Hsieh, T J]] | |||
[[Category: Lin, C H]] | |||
[[Category: Lin, H Y]] | |||
[[Category: Complex]] | |||
[[Category: Galectin-1]] | |||
[[Category: Lectin]] | |||
[[Category: Neuacalpha2-3galbeta1-4glc]] | |||
[[Category: Sugar binding protein]] |