4d50: Difference between revisions

← Older edit Newer edit →

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+==Structure of human deoxyhypusine hydroxylase==
+<StructureSection load='4d50' size='340' side='right' caption='[[4d50]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
-The entry 4d50 is ON HOLD  until Paper Publication
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4d50]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D50 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4D50 FirstGlance]. <br>
-Authors: Han, Z., Sakai, N., Hilgenfeld, R.
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=GAI:GUANIDINE'>GAI</scene>, <scene name='pdbligand=PER:PEROXIDE+ION'>PER</scene></td></tr>
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4d4z|4d4z]]</td></tr>
-Description: Structure of human deoxyhypusine hydroxylase
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Deoxyhypusine_monooxygenase Deoxyhypusine monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.99.29 1.14.99.29] </span></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4d50 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d50 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4d50 RCSB], [http://www.ebi.ac.uk/pdbsum/4d50 PDBsum]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/DOHH_HUMAN DOHH_HUMAN]] Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.[HAMAP-Rule:MF_03101]<ref>PMID:16371467</ref> <ref>PMID:19706422</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Deoxyhypusine monooxygenase]]
+[[Category: Han, Z]]
 [[Category: Hilgenfeld, R]]
-[[Category: Han, Z]]
 [[Category: Sakai, N]]
+[[Category: Oxidoreductase]]