Sandbox Reserved 1077: Difference between revisions

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OCA, Geoffrey C. Hoops

Revision as of 03:27, 1 April 2015 view source Geoffrey C. Hoops (talk \| contribs) 208 edits No edit summary ← Older edit		Revision as of 03:51, 1 April 2015 view source Geoffrey C. Hoops (talk \| contribs) 208 edits No edit summary Newer edit →
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	The <scene name='69/694244/Secondary_structure/1'>secondary structure</scene> of this enzyme is typical of α/β hydrolases		The <scene name='69/694244/Secondary_structure/1'>secondary structure</scene> of this enzyme is typical of α/β hydrolases

	The structure solved by x-ray crystallography<ref>PMID:21637775</ref> was missing the <scene name='69/694244/Glu38/1'>N-terminal</scene> 37 residues as well as a <scene name='69/694244/Glu193_and_arg205/3'>flexible loop</scene> (residues 194-204). A theoretical [http://falc-loop.seoklab.org/ FALC-loop]<ref>PMID:21576220</ref> model for this flexible loop is supported by the relative activities of alanine variants of the individual residues 194-204<ref>PMID:25354081</ref>.		The structure solved by x-ray crystallography<ref>PMID:21637775</ref> was missing the <scene name='69/694244/Glu38/1'>N-terminal</scene> 37 residues as well as a <scene name='69/694244/Glu193_and_arg205/3'>flexible loop</scene> (residues 194-204). A theoretical [http://falc-loop.seoklab.org/ FALC-loop]<ref>PMID:21576220</ref> <scene name='69/694244/Loop_modeled_backbone_view/1'>model</scene>for this flexible loop is supported by the relative activities of alanine variants of the individual residues 194-204<ref>PMID:25354081</ref>.