2qqd: Difference between revisions

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 |PDB= 2qqd |SIZE=350|CAPTION= <scene name='initialview01'>2qqd</scene>, resolution 2.00&Aring;
 |SITE= <scene name='pdbsite=AC1:Ag2+Binding+Site+For+Residue+B+671'>AC1</scene>, <scene name='pdbsite=AC2:Ag2+Binding+Site+For+Residue+A+671'>AC2</scene>, <scene name='pdbsite=AC3:Pyr+Binding+Site+For+Residue+B+53'>AC3</scene>, <scene name='pdbsite=AC4:Pyr+Binding+Site+For+Residue+E+53'>AC4</scene>, <scene name='pdbsite=AC5:Mpd+Binding+Site+For+Residue+C+700'>AC5</scene> and <scene name='pdbsite=AC6:Mpd+Binding+Site+For+Residue+D+700'>AC6</scene>
-|LIGAND= <scene name='pdbligand=AG2:AGMATINE'>AG2</scene>, <scene name='pdbligand=PYR:PYRUVIC+ACID'>PYR</scene> and <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>
+|LIGAND= <scene name='pdbligand=AG2:AGMATINE'>AG2</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=PYR:PYRUVIC+ACID'>PYR</scene>
-|ACTIVITY= [http://en.wikipedia.org/wiki/Arginine_decarboxylase Arginine decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.19 4.1.1.19]
+|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Arginine_decarboxylase Arginine decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.19 4.1.1.19] </span>
 |GENE= pdaD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2190 Methanocaldococcus jannaschii])
+|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG1945 COG1945], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=PRK01285 PRK01285]</span>
+|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qqd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qqd OCA], [http://www.ebi.ac.uk/pdbsum/2qqd PDBsum], [http://www.fli-leibniz.de/cgi-bin/ImgLib.pl?CODE=1kfv JenaLib], [http://www.rcsb.org/pdb/explore.do?structureId=2qqd RCSB]</span>
 }}
 '''N47A mutant of Pyruvoyl-dependent Arginine Decarboxylase from Methanococcus jannashii'''
-==Overview==
-Human deoxycytidine kinase (dCK) is involved in the nucleotide-biosynthesis salvage pathway and has also been shown to phosphorylate several antitumor and antiviral prodrugs. The structures of dCK alone and the dead-end complex of dCK with substrate nucleoside and product ADP or UDP have previously been reported; however, there is currently no structure available for a substrate or product complex. Here, the structures of dCK complexes with the products dCMP, UDP and Mg2+ ion, and with dAMP, UDP and Mg2+ ion are reported. Structural comparisons show that the product complexes with UDP and a dead-end complex with substrate and UDP have similar active-site conformations.
 ==About this Structure==
 QQD is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QQD OCA].
-==Reference==
-Structures of human deoxycytidine kinase product complexes., Soriano EV, Clark VC, Ealick SE, Acta Crystallogr D Biol Crystallogr. 2007 Dec;63(Pt 12):1201-7. Epub 2007, Nov 16. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18084067 18084067]
 [[Category: Arginine decarboxylase]]
 [[Category: Methanocaldococcus jannaschii]]
@@ Line 25: / Line 21: @@
 [[Category: Ealick, S E.]]
 [[Category: Soriano, E S.]]
-[[Category: AG2]]
-[[Category: MPD]]
-[[Category: PYR]]
 [[Category: arginine decarboxylase]]
 [[Category: autoprocessing]]
@@ Line 36: / Line 29: @@
 [[Category: serinolysis]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:28:34 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 26 10:02:39 2008''