2pip: Difference between revisions

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|PDB= 2pip |SIZE=350|CAPTION= <scene name='initialview01'>2pip</scene>, resolution 1.8&Aring;
|PDB= 2pip |SIZE=350|CAPTION= <scene name='initialview01'>2pip</scene>, resolution 1.8&Aring;
|SITE=  
|SITE=  
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=DHT:DIHYDROTESTOSTERONE'>DHT</scene>, <scene name='pdbligand=ICO:1H-INDOLE-3-CARBOXYLIC+ACID'>ICO</scene> and <scene name='pdbligand=K10:1-TERT-BUTYL-3-(2,5-DIMETHYLBENZYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE'>K10</scene>
|LIGAND= <scene name='pdbligand=DHT:DIHYDROTESTOSTERONE'>DHT</scene>, <scene name='pdbligand=ICO:1H-INDOLE-3-CARBOXYLIC+ACID'>ICO</scene>, <scene name='pdbligand=K10:1-TERT-BUTYL-3-(2,5-DIMETHYLBENZYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE'>K10</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
|ACTIVITY=  
|ACTIVITY=  
|GENE= AR, DHTR, NR3C4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
|GENE= AR, DHTR, NR3C4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
|DOMAIN=
|RELATEDENTRY=[[2pin|2PIN]], [[2pio|2PIO]], [[2piq|2PIQ]], [[2pir|2PIR]], [[2pit|2PIT]], [[2piu|2PIU]], [[2piv|2PIV]], [[2piw|2PIW]], [[2pix|2PIX]], [[2pkl|2PKL]]
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pip FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pip OCA], [http://www.ebi.ac.uk/pdbsum/2pip PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2pip RCSB]</span>
}}
}}


'''Androgen receptor LBD with small molecule'''
'''Androgen receptor LBD with small molecule'''


==Disease==
Known diseases associated with this structure: Androgen insensitivity OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=313700 313700]], Breast cancer, male, with Reifenstein syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=313700 313700]], Hypospadias, perineal OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=313700 313700]], Prostate cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=313700 313700]], Prostate cancer, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=313700 313700]], Spinal and bulbar muscular atrophy of Kennedy OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=313700 313700]]


==About this Structure==
==About this Structure==
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[[Category: Guy, R K.]]
[[Category: Guy, R K.]]
[[Category: Webb, P.]]
[[Category: Webb, P.]]
[[Category: DHT]]
[[Category: ICO]]
[[Category: K10]]
[[Category: SO4]]
[[Category: af-2 pocket]]
[[Category: af-2 pocket]]
[[Category: androgen receptor]]
[[Category: androgen receptor]]
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[[Category: inhibitor]]
[[Category: inhibitor]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:13:28 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:36:31 2008''

Revision as of 04:36, 31 March 2008

File:2pip.jpg


PDB ID 2pip

Drag the structure with the mouse to rotate
, resolution 1.8Å
Ligands: , , ,
Gene: AR, DHTR, NR3C4 (Homo sapiens)
Related: 2PIN, 2PIO, 2PIQ, 2PIR, 2PIT, 2PIU, 2PIV, 2PIW, 2PIX, 2PKL


Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



Androgen receptor LBD with small molecule


About this StructureAbout this Structure

2PIP is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Page seeded by OCA on Mon Mar 31 04:36:31 2008

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