2k6v: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
← Older editNewer edit →
No edit summary
No edit summary
Line 2: Line 2:
<StructureSection load='2k6v' size='340' side='right' caption='[[2k6v]], [[NMR_Ensembles_of_Models | 31 NMR models]]' scene=''>
<StructureSection load='2k6v' size='340' side='right' caption='[[2k6v]], [[NMR_Ensembles_of_Models | 31 NMR models]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2k6v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K6V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2K6V FirstGlance]. <br>
<table><tr><td colspan='2'>[[2k6v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thet8 Thet8]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K6V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2K6V FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2k6w|2k6w]], [[2k6y|2k6y]], [[2k6z|2k6z]], [[2k70|2k70]]</td></tr>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2k6w|2k6w]], [[2k6y|2k6y]], [[2k6z|2k6z]], [[2k70|2k70]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TTHA1942 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=274 Thermus thermophilus])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TTHA1942 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=300852 THET8])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2k6v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k6v OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2k6v RCSB], [http://www.ebi.ac.uk/pdbsum/2k6v PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2k6v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k6v OCA], [http://pdbe.org/2k6v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2k6v RCSB], [http://www.ebi.ac.uk/pdbsum/2k6v PDBsum]</span></td></tr>
</table>
</table>
{{Large structure}}
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 25: Line 26:
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 2k6v" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Thermus thermophilus]]
[[Category: Thet8]]
[[Category: Abriata, L A]]
[[Category: Abriata, L A]]
[[Category: Banci, L]]
[[Category: Banci, L]]

Revision as of 14:34, 11 September 2015

Solution structures of apo Sco1 protein from Thermus ThermophilusSolution structures of apo Sco1 protein from Thermus Thermophilus

Structural highlights

2k6v is a 1 chain structure with sequence from Thet8. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Gene:TTHA1942 (THET8)
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum
Warning: this is a large structure, and loading might take a long time or not happen at all.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

Publication Abstract from PubMed

Copper is essential for proper functioning of cytochrome c oxidases, and therefore for cellular respiration in eukaryotes and many bacteria. Here we show that a new periplasmic protein (PCu(A)C) selectively inserts Cu(I) ions into subunit II of Thermus thermophilus ba(3) oxidase to generate a native Cu(A) site. The purported metallochaperone Sco1 is unable to deliver copper ions; instead, it works as a thiol-disulfide reductase to maintain the correct oxidation state of the Cu(A) cysteine ligands.

Mechanism of Cu(A) assembly.,Abriata LA, Banci L, Bertini I, Ciofi-Baffoni S, Gkazonis P, Spyroulias GA, Vila AJ, Wang S Nat Chem Biol. 2008 Oct;4(10):599-601. Epub 2008 Aug 31. PMID:18758441[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

References

  1. ↑ Abriata LA, Banci L, Bertini I, Ciofi-Baffoni S, Gkazonis P, Spyroulias GA, Vila AJ, Wang S. Mechanism of Cu(A) assembly. Nat Chem Biol. 2008 Oct;4(10):599-601. Epub 2008 Aug 31. PMID:18758441 doi:10.1038/nchembio.110
Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
Retrieved from "https://proteopedia.openfox.io/wiki/index.php?title=2k6v&oldid=2475961"