2jhp: Difference between revisions
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|PDB= 2jhp |SIZE=350|CAPTION= <scene name='initialview01'>2jhp</scene>, resolution 2.50Å | |PDB= 2jhp |SIZE=350|CAPTION= <scene name='initialview01'>2jhp</scene>, resolution 2.50Å | ||
|SITE= <scene name='pdbsite=AC1:Gun+Binding+Site+For+Chain+A'>AC1</scene> | |SITE= <scene name='pdbsite=AC1:Gun+Binding+Site+For+Chain+A'>AC1</scene> | ||
|LIGAND= <scene name='pdbligand= | |LIGAND= <scene name='pdbligand=GUN:GUANINE'>GUN</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene> | ||
|ACTIVITY= | |ACTIVITY= | ||
|GENE= | |GENE= | ||
|DOMAIN= | |||
|RELATEDENTRY= | |||
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jhp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jhp OCA], [http://www.ebi.ac.uk/pdbsum/2jhp PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2jhp RCSB]</span> | |||
}} | }} | ||
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[[Category: Stuart, D I.]] | [[Category: Stuart, D I.]] | ||
[[Category: Sutton, G.]] | [[Category: Sutton, G.]] | ||
[[Category: core protein]] | [[Category: core protein]] | ||
[[Category: guanylyltransferase]] | [[Category: guanylyltransferase]] | ||
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[[Category: virion protein]] | [[Category: virion protein]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:58:21 2008'' | ||
Revision as of 03:58, 31 March 2008
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| , resolution 2.50Å | |||||||
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| Ligands: | , | ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
THE STRUCTURE OF BLUETONGUE VIRUS VP4 REVEALS A MULTIFUNCTIONAL RNA-CAPPING PRODUCTION-LINE
OverviewOverview
Eukaryotic organisms cap the 5' ends of their messenger RNAs by a series of four chemical reactions. Some viruses achieve this using a single molecule; the crystal structure of such an enzyme from bluetongue virus reveals an elongated modular architecture that provides a scaffold for an assemblage of active sites, two contributed by a domain of novel structure.
About this StructureAbout this Structure
2JHP is a Single protein structure of sequence from Bluetongue virus 10 (isolate usa). Full crystallographic information is available from OCA.
ReferenceReference
Bluetongue virus VP4 is an RNA-capping assembly line., Sutton G, Grimes JM, Stuart DI, Roy P, Nat Struct Mol Biol. 2007 May;14(5):449-51. Epub 2007 Apr 8. PMID:17417654
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