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== Inhibition ==
== Inhibition ==
In the treatment erection dysfunction, the inhibitors Sildenafil, Vardenafil and Tadalafil are used, like in the pulmonary hypertension<ref>[6]</ref>. Sildenafil may cure sleeping trouble after a intercontinental travel <ref>[11]</ref>, may help to recover neural liaisons after an injury (the motor function<ref>[12]</ref> and the sensory motor function<ref>[13]</ref>) and can be vascular effects.<br \>[[Image:Sildenafil.jpg|center|thumb|100px|Sildenafil Inhibitor, R1 in blue, R2 in green and R3 in red]]
In the treatment erection dysfunction, the inhibitors Sildenafil, Vardenafil and Tadalafil are used, like in the pulmonary hypertension<ref>[6]</ref>. Sildenafil may cure sleeping trouble after a intercontinental travel <ref>[11]</ref>, may help to recover neural liaisons after an injury (the motor function<ref>[12]</ref> and the sensory motor function<ref>[13]</ref>) and can be vascular effects.<br \>
<gallery>Image:Sildenafil.jpg|500px|Sildenafil Inhibitor, R1 in blue, R2 in green and R3 in red
Image:Sildenafilspace.jpg|500px|Sildenafil Inhibitor in the space in the enzyme</gallery>


* PDE5 inhibitors might help physical condition in Duchene muscular dystrophy<ref>[14]</ref>, improve of cognitive function <ref>[9]</ref>and have antidepressant effect<ref>[10]</ref> , also they might have an artero<ref>[15]</ref> and endothelial cell protective effect<ref>[16]</ref> so they have cardiac protection effect<ref>[17]</ref> (controversial, cf. clinical trial “RELAX”), finally they slow tumer cell growth (Tadalafil-like)[18]<br \>
* PDE5 inhibitors might help physical condition in Duchene muscular dystrophy<ref>[14]</ref>, improve of cognitive function <ref>[9]</ref>and have antidepressant effect<ref>[10]</ref> , also they might have an artero<ref>[15]</ref> and endothelial cell protective effect<ref>[16]</ref> so they have cardiac protection effect<ref>[17]</ref> (controversial, cf. clinical trial “RELAX”), finally they slow tumer cell growth (Tadalafil-like)[18]<br \>

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OCA, Michael Pierrelee