4dhy: Difference between revisions

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==Crystal structure of human glucokinase in complex with glucose and activator==
==Crystal structure of human glucokinase in complex with glucose and activator==
<StructureSection load='4dhy' size='340' side='right' caption='[[4dhy]], [[Resolution|resolution]] 2.38&Aring;' scene=''>
<StructureSection load='4dhy' size='340' side='right' caption='[[4dhy]], [[Resolution|resolution]] 2.38&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4dhy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DHY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4DHY FirstGlance]. <br>
<table><tr><td colspan='2'>[[4dhy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DHY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4DHY FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=S41:N,N-DIMETHYL-5-({2-METHYL-6-[(5-METHYLPYRAZIN-2-YL)CARBAMOYL]-1-BENZOFURAN-4-YL}OXY)PYRIMIDINE-2-CARBOXAMIDE'>S41</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=S41:N,N-DIMETHYL-5-({2-METHYL-6-[(5-METHYLPYRAZIN-2-YL)CARBAMOYL]-1-BENZOFURAN-4-YL}OXY)PYRIMIDINE-2-CARBOXAMIDE'>S41</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3s41|3s41]], [[3vev|3vev]], [[3ve6|3ve6]], [[3vf6|3vf6]], [[4dch|4dch]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3s41|3s41]], [[3vev|3vev]], [[3ve6|3ve6]], [[3vf6|3vf6]], [[4dch|4dch]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GCK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GCK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4dhy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dhy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4dhy RCSB], [http://www.ebi.ac.uk/pdbsum/4dhy PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4dhy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dhy OCA], [http://pdbe.org/4dhy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4dhy RCSB], [http://www.ebi.ac.uk/pdbsum/4dhy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4dhy ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4dhy" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
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</StructureSection>
</StructureSection>
[[Category: Glucokinase]]
[[Category: Glucokinase]]
[[Category: Homo sapiens]]
[[Category: Human]]
[[Category: Liu, S]]
[[Category: Liu, S]]
[[Category: Diabetes mellitus]]
[[Category: Diabetes mellitus]]

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