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==Crystal structure of wild-type HIV-1 protease in complex with AF69== | ==Crystal structure of wild-type HIV-1 protease in complex with AF69== | ||
<StructureSection load='3sa5' size='340' side='right' caption='[[3sa5]], [[Resolution|resolution]] 1.65Å' scene=''> | <StructureSection load='3sa5' size='340' side='right' caption='[[3sa5]], [[Resolution|resolution]] 1.65Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3sa5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[3sa5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/9hiv1 9hiv1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SA5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3SA5 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=A69:N-{(2S,3R)-4-[(1,3-BENZOTHIAZOL-6-YLSULFONYL)(3-PHENYLPROPYL)AMINO]-3-HYDROXY-1-PHENYLBUTAN-2-YL}-3-HYDROXYBENZAMIDE'>A69</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=A69:N-{(2S,3R)-4-[(1,3-BENZOTHIAZOL-6-YLSULFONYL)(3-PHENYLPROPYL)AMINO]-3-HYDROXY-1-PHENYLBUTAN-2-YL}-3-HYDROXYBENZAMIDE'>A69</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3sa3|3sa3]], [[3sa4|3sa4]], [[3sa6|3sa6]], [[3sa7|3sa7]], [[3sa8|3sa8]], [[3sa9|3sa9]], [[3saa|3saa]], [[3sab|3sab]], [[3sac|3sac]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3sa3|3sa3]], [[3sa4|3sa4]], [[3sa6|3sa6]], [[3sa7|3sa7]], [[3sa8|3sa8]], [[3sa9|3sa9]], [[3saa|3saa]], [[3sab|3sab]], [[3sac|3sac]]</td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gag-pol, pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gag-pol, pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 9HIV1])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3sa5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sa5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3sa5 RCSB], [http://www.ebi.ac.uk/pdbsum/3sa5 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3sa5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sa5 OCA], [http://pdbe.org/3sa5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3sa5 RCSB], [http://www.ebi.ac.uk/pdbsum/3sa5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3sa5 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Nalam, M N.L]] | [[Category: Nalam, M N.L]] | ||
[[Category: Schiffer, C A]] | [[Category: Schiffer, C A]] | ||
Revision as of 11:42, 11 August 2016
Crystal structure of wild-type HIV-1 protease in complex with AF69Crystal structure of wild-type HIV-1 protease in complex with AF69
Structural highlights
See Also |
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