2gic: Difference between revisions
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|PDB= 2gic |SIZE=350|CAPTION= <scene name='initialview01'>2gic</scene>, resolution 2.920Å | |PDB= 2gic |SIZE=350|CAPTION= <scene name='initialview01'>2gic</scene>, resolution 2.920Å | ||
|SITE= | |SITE= | ||
|LIGAND= <scene name='pdbligand=IUM:URANYL (VI) ION'>IUM</scene> | |LIGAND= <scene name='pdbligand=IUM:URANYL+(VI)+ION'>IUM</scene>, <scene name='pdbligand=U:URIDINE-5'-MONOPHOSPHATE'>U</scene> | ||
|ACTIVITY= | |ACTIVITY= | ||
|GENE= N ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11277 Vesicular stomatitis Indiana virus]) | |GENE= N ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11277 Vesicular stomatitis Indiana virus]) | ||
|DOMAIN= | |||
|RELATEDENTRY= | |||
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gic FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gic OCA], [http://www.ebi.ac.uk/pdbsum/2gic PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2gic RCSB]</span> | |||
}} | }} | ||
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[[Category: Wertz, G W.]] | [[Category: Wertz, G W.]] | ||
[[Category: Zhang, X.]] | [[Category: Zhang, X.]] | ||
[[Category: negative strand virus]] | [[Category: negative strand virus]] | ||
[[Category: nucleocapsid]] | [[Category: nucleocapsid]] | ||
[[Category: protein-rna complex]] | [[Category: protein-rna complex]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:16:59 2008'' | ||
Revision as of 03:16, 31 March 2008
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| , resolution 2.920Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | , | ||||||
| Gene: | N (Vesicular stomatitis Indiana virus) | ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Crystal Structure of a vesicular stomatitis virus nucleocapsid-RNA complex
OverviewOverview
Vesicular stomatitis virus is a negative-stranded RNA virus. Its nucleoprotein (N) binds the viral genomic RNA and is involved in multiple functions including transcription, replication, and assembly. We have determined a 2.9 angstrom structure of a complex containing 10 molecules of the N protein and 90 bases of RNA. The RNA is tightly sequestered in a cavity at the interface between two lobes of the N protein. This serves to protect the RNA in the absence of polynucleotide synthesis. For the RNA to be accessed, some conformational change in the N protein should be necessary.
About this StructureAbout this Structure
2GIC is a Single protein structure of sequence from Vesicular stomatitis indiana virus. Full crystallographic information is available from OCA.
ReferenceReference
Structure of the vesicular stomatitis virus nucleoprotein-RNA complex., Green TJ, Zhang X, Wertz GW, Luo M, Science. 2006 Jul 21;313(5785):357-60. Epub 2006 Jun 15. PMID:16778022
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