2g6p: Difference between revisions

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|PDB= 2g6p |SIZE=350|CAPTION= <scene name='initialview01'>2g6p</scene>, resolution 1.90&Aring;
|PDB= 2g6p |SIZE=350|CAPTION= <scene name='initialview01'>2g6p</scene>, resolution 1.90&Aring;
|SITE=  
|SITE=  
|LIGAND= <scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=HM2:5-CHLORO-6-METHYL-N-(2-PHENYLETHYL)-2-PYRIDIN-2-YLPYRIMIDIN-4-AMINE'>HM2</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
|LIGAND= <scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HM2:5-CHLORO-6-METHYL-N-(2-PHENYLETHYL)-2-PYRIDIN-2-YLPYRIMIDIN-4-AMINE'>HM2</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Methionyl_aminopeptidase Methionyl aminopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.11.18 3.4.11.18]  
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Methionyl_aminopeptidase Methionyl aminopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.11.18 3.4.11.18] </span>
|GENE= METAP1, KIAA0094 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
|GENE= METAP1, KIAA0094 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
|DOMAIN=
|RELATEDENTRY=[[2b3h|2B3H]]
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2g6p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g6p OCA], [http://www.ebi.ac.uk/pdbsum/2g6p PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2g6p RCSB]</span>
}}
}}


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[[Category: Liu, J O.]]
[[Category: Liu, J O.]]
[[Category: Matthews, B W.]]
[[Category: Matthews, B W.]]
[[Category: CO]]
[[Category: EPE]]
[[Category: GOL]]
[[Category: HM2]]
[[Category: K]]
[[Category: hydrolase]]
[[Category: hydrolase]]
[[Category: methionine aminopeptidase]]
[[Category: methionine aminopeptidase]]
[[Category: pyridinyl pyrimidine]]
[[Category: pyridinyl pyrimidine]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:01:06 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:12:36 2008''

Revision as of 03:12, 31 March 2008

File:2g6p.gif


PDB ID 2g6p

Drag the structure with the mouse to rotate
, resolution 1.90Å
Ligands: , , , ,
Gene: METAP1, KIAA0094 (Homo sapiens)
Activity: Methionyl aminopeptidase, with EC number 3.4.11.18
Related: 2B3H


Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



Crystal structure of truncated (delta 1-89) human methionine aminopeptidase Type 1 in complex with Pyridyl pyrimidine derivative


About this StructureAbout this Structure

2G6P is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

Identification of pyridinylpyrimidines as inhibitors of human methionine aminopeptidases., Hu X, Addlagatta A, Matthews BW, Liu JO, Angew Chem Int Ed Engl. 2006 Jun 2;45(23):3772-5. PMID:16724298

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