2g5o: Difference between revisions

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|PDB= 2g5o |SIZE=350|CAPTION= <scene name='initialview01'>2g5o</scene>, resolution 2.30&Aring;
|PDB= 2g5o |SIZE=350|CAPTION= <scene name='initialview01'>2g5o</scene>, resolution 2.30&Aring;
|SITE=  
|SITE=  
|LIGAND= <scene name='pdbligand=DRQ:(9ALPHA,13BETA,17BETA)-2-[(1Z)-BUT-1-EN-1-YL]ESTRA-1,3,5(10)-TRIENE-3,17-DIOL'>DRQ</scene>
|LIGAND= <scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene>, <scene name='pdbligand=DRQ:(9ALPHA,13BETA,17BETA)-2-[(1Z)-BUT-1-EN-1-YL]ESTRA-1,3,5(10)-TRIENE-3,17-DIOL'>DRQ</scene>
|ACTIVITY=  
|ACTIVITY=  
|GENE= ESR1, ESR, NR3A1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
|GENE= ESR1, ESR, NR3A1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
|DOMAIN=
|RELATEDENTRY=[[2g44|2G44]]
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2g5o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g5o OCA], [http://www.ebi.ac.uk/pdbsum/2g5o PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2g5o RCSB]</span>
}}
}}


'''Human estrogen receptor alpha ligand-binding domain in complex with 2-(but-1-enyl)-17beta-estradiol and a glucocorticoid receptor interacting protein 1 NR BOX II Peptide'''
'''Human estrogen receptor alpha ligand-binding domain in complex with 2-(but-1-enyl)-17beta-estradiol and a glucocorticoid receptor interacting protein 1 NR BOX II Peptide'''


==Disease==
Known diseases associated with this structure: Atherosclerosis, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=133430 133430]], Breast cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=133430 133430]], Estrogen resistance OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=133430 133430]], HDL response to hormone replacement, augmented OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=133430 133430]], Migraine, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=133430 133430]], Myocardial infarction, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=133430 133430]]


==About this Structure==
==About this Structure==
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[[Category: Rajan, S S.]]
[[Category: Rajan, S S.]]
[[Category: Sharma, S K.]]
[[Category: Sharma, S K.]]
[[Category: DRQ]]
[[Category: estrogen receptor]]
[[Category: estrogen receptor]]
[[Category: grip peptide]]
[[Category: grip peptide]]
[[Category: lbd]]
[[Category: lbd]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:00:44 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:12:08 2008''

Revision as of 03:12, 31 March 2008

File:2g5o.gif


PDB ID 2g5o

Drag the structure with the mouse to rotate
, resolution 2.30Å
Ligands: ,
Gene: ESR1, ESR, NR3A1 (Homo sapiens)
Related: 2G44


Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



Human estrogen receptor alpha ligand-binding domain in complex with 2-(but-1-enyl)-17beta-estradiol and a glucocorticoid receptor interacting protein 1 NR BOX II Peptide


About this StructureAbout this Structure

2G5O is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Page seeded by OCA on Mon Mar 31 03:12:08 2008

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