1pee: Difference between revisions
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<StructureSection load='1pee' size='340' side='right' caption='[[1pee]], [[Resolution|resolution]] 1.50Å' scene=''> | <StructureSection load='1pee' size='340' side='right' caption='[[1pee]], [[Resolution|resolution]] 1.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1pee]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[1pee]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhopr Rhopr]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PEE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1PEE FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1euo|1euo]], [[1ikj|1ikj]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1euo|1euo]], [[1ikj|1ikj]]</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1pee FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pee OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1pee RCSB], [http://www.ebi.ac.uk/pdbsum/1pee PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1pee FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pee OCA], [http://pdbe.org/1pee PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1pee RCSB], [http://www.ebi.ac.uk/pdbsum/1pee PDBsum]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Rhopr]] | ||
[[Category: Montfort, W R]] | [[Category: Montfort, W R]] | ||
[[Category: Weihsel, A]] | [[Category: Weihsel, A]] | ||
Revision as of 05:31, 12 September 2015
Crystal Structure of Nitrophorin 2 complex with imidazoleCrystal Structure of Nitrophorin 2 complex with imidazole
Structural highlights
Function[NP2_RHOPR] Heme-based protein that deliver nitric oxide gas (NO) to the victim while feeding, resulting in vasodilation and inhibition of platelet aggregation. Also bind tightly to histamine, which is released by the host to induce wound healing (By similarity). Specifically inhibits factor IXa-catalyzed activation of factor X in the presence of calcium and phospholipids irrespective of the presence or absence of factor VIIIa. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. |
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