2k16: Difference between revisions

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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2k17|2k17]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2k17|2k17]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Taf3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Taf3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2k16 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k16 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2k16 RCSB], [http://www.ebi.ac.uk/pdbsum/2k16 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2k16 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k16 OCA], [http://pdbe.org/2k16 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2k16 RCSB], [http://www.ebi.ac.uk/pdbsum/2k16 PDBsum]</span></td></tr>
</table>
</table>
== Function ==
== Function ==

Revision as of 03:42, 12 September 2015

Solution structure of the free TAF3 PHD domainSolution structure of the free TAF3 PHD domain

Structural highlights

2k16 is a 1 chain structure with sequence from Mus musculus. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Gene:Taf3 (Mus musculus)
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum

Function

[TAF3_MOUSE] Transcription factor TFIID is one of the general factors required for accurate and regulated initiation by RNA polymerase II. TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. Required in complex with TBPL2 for the differentiation of myoblasts into myocytes. The complex replaces TFIID at specific promoters at an early stage in the differentiation process.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. ↑ Deato MD, Tjian R. Switching of the core transcription machinery during myogenesis. Genes Dev. 2007 Sep 1;21(17):2137-49. Epub 2007 Aug 17. PMID:17704303 doi:http://dx.doi.org/10.1101/gad.1583407
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