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==The zinc ion bound form of crystal structure of E.coli ExoI-ssDNA complex==
==The zinc ion bound form of crystal structure of E.coli ExoI-ssDNA complex==
<StructureSection load='4hcc' size='340' side='right' caption='[[4hcc]], [[Resolution|resolution]] 2.96&Aring;' scene=''>
<StructureSection load='4hcc' size='340' side='right' caption='[[4hcc]], [[Resolution|resolution]] 2.96&Aring;' scene=''>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">b2011, cpeA, JW1993, sbcB, xonA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=668369 Escherichia coli DH5[alpha]])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">b2011, cpeA, JW1993, sbcB, xonA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=668369 Escherichia coli DH5[alpha]])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Exodeoxyribonuclease_I Exodeoxyribonuclease I], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.11.1 3.1.11.1] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Exodeoxyribonuclease_I Exodeoxyribonuclease I], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.11.1 3.1.11.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hcc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hcc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4hcc RCSB], [http://www.ebi.ac.uk/pdbsum/4hcc PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hcc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hcc OCA], [http://pdbe.org/4hcc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4hcc RCSB], [http://www.ebi.ac.uk/pdbsum/4hcc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4hcc ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==

Revision as of 21:09, 5 August 2016

The zinc ion bound form of crystal structure of E.coli ExoI-ssDNA complexThe zinc ion bound form of crystal structure of E.coli ExoI-ssDNA complex

Structural highlights

4hcc is a 4 chain structure with sequence from [alpha Escherichia coli dh5[alpha]]. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, , ,
Gene:b2011, cpeA, JW1993, sbcB, xonA (Escherichia coli DH5[alpha])
Activity:Exodeoxyribonuclease I, with EC number 3.1.11.1
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[EX1_ECOLI] Also functions as a DNA deoxyribophosphodiesterase that releases deoxyribose-phosphate moieties following the cleavage DNA at an apurinic/apyrimidinic (AP) site by either an AP endonuclease AP lyase.

4hcc, resolution 2.96Å

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