3avl: Difference between revisions

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==Crystal structures of novel allosteric peptide inhibitors of HIV integrase in the LEDGF binding site==
==Crystal structures of novel allosteric peptide inhibitors of HIV integrase in the LEDGF binding site==
<StructureSection load='3avl' size='340' side='right' caption='[[3avl]], [[Resolution|resolution]] 1.88&Aring;' scene=''>
<StructureSection load='3avl' size='340' side='right' caption='[[3avl]], [[Resolution|resolution]] 1.88&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3avl]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_type_1_(new_york-5_isolate) Human immunodeficiency virus type 1 (new york-5 isolate)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AVL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3AVL FirstGlance]. <br>
<table><tr><td colspan='2'>[[3avl]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Hiv-1 Hiv-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AVL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3AVL FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3av9|3av9]], [[3ava|3ava]], [[3avb|3avb]], [[3avc|3avc]], [[3avf|3avf]], [[3avg|3avg]], [[3avh|3avh]], [[3avi|3avi]], [[3avj|3avj]], [[3avk|3avk]], [[3avm|3avm]], [[3avn|3avn]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3av9|3av9]], [[3ava|3ava]], [[3avb|3avb]], [[3avc|3avc]], [[3avf|3avf]], [[3avg|3avg]], [[3avh|3avh]], [[3avi|3avi]], [[3avj|3avj]], [[3avk|3avk]], [[3avm|3avm]], [[3avn|3avn]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gag-pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11698 Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE)])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gag-pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11698 HIV-1])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3avl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3avl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3avl RCSB], [http://www.ebi.ac.uk/pdbsum/3avl PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3avl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3avl OCA], [http://pdbe.org/3avl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3avl RCSB], [http://www.ebi.ac.uk/pdbsum/3avl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3avl ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 3avl" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
*[[HIV integrase|HIV integrase]]
*[[Retroviral Integrase|Retroviral Integrase]]
*[[Retroviral Integrase|Retroviral Integrase]]
== References ==
== References ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Hiv-1]]
[[Category: Deadman, J J]]
[[Category: Deadman, J J]]
[[Category: Newman, J]]
[[Category: Newman, J]]

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