4ol9: Difference between revisions

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==Crystal Structure of putative 2-dehydropantoate 2-reductase PanE from Mycobacterium tuberculosis complexed with NADP and oxamate==
==Crystal Structure of putative 2-dehydropantoate 2-reductase PanE from Mycobacterium tuberculosis complexed with NADP and oxamate==
<StructureSection load='4ol9' size='340' side='right' caption='[[4ol9]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
<StructureSection load='4ol9' size='340' side='right' caption='[[4ol9]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Rv2573, MT2649, MTCY227.28c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Rv2573, MT2649, MTCY227.28c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/2-dehydropantoate_2-reductase 2-dehydropantoate 2-reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.169 1.1.1.169] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/2-dehydropantoate_2-reductase 2-dehydropantoate 2-reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.169 1.1.1.169] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ol9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ol9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ol9 RCSB], [http://www.ebi.ac.uk/pdbsum/4ol9 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ol9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ol9 OCA], [http://pdbe.org/4ol9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ol9 RCSB], [http://www.ebi.ac.uk/pdbsum/4ol9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ol9 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==

Revision as of 14:43, 5 August 2016

Crystal Structure of putative 2-dehydropantoate 2-reductase PanE from Mycobacterium tuberculosis complexed with NADP and oxamateCrystal Structure of putative 2-dehydropantoate 2-reductase PanE from Mycobacterium tuberculosis complexed with NADP and oxamate

Structural highlights

4ol9 is a 1 chain structure with sequence from "bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, , , ,
Gene:Rv2573, MT2649, MTCY227.28c ("Bacillus tuberculosis" (Zopf 1883) Klein 1884)
Activity:2-dehydropantoate 2-reductase, with EC number 1.1.1.169
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[PANE_MYCTU] Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity).

4ol9, resolution 1.85Å

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