3u10: Difference between revisions
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
==Tetramerization dynamics of the C-terminus underlies isoform-specific cAMP-gating in HCN channels== | ==Tetramerization dynamics of the C-terminus underlies isoform-specific cAMP-gating in HCN channels== | ||
<StructureSection load='3u10' size='340' side='right' caption='[[3u10]], [[Resolution|resolution]] 2.30Å' scene=''> | <StructureSection load='3u10' size='340' side='right' caption='[[3u10]], [[Resolution|resolution]] 2.30Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3u10]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[3u10]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U10 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3U10 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CMP:ADENOSINE-3,5-CYCLIC-MONOPHOSPHATE'>CMP</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CMP:ADENOSINE-3,5-CYCLIC-MONOPHOSPHATE'>CMP</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3u0z|3u0z]], [[3u11|3u11]], [[1q43|1q43]], [[3otf|3otf]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3u0z|3u0z]], [[3u11|3u11]], [[1q43|1q43]], [[3otf|3otf]]</td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HCN2, BCNG2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HCN2, BCNG2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3u10 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u10 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3u10 RCSB], [http://www.ebi.ac.uk/pdbsum/3u10 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3u10 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u10 OCA], [http://pdbe.org/3u10 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3u10 RCSB], [http://www.ebi.ac.uk/pdbsum/3u10 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3u10 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| Line 18: | Line 19: | ||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 3u10" style="background-color:#fffaf0;"></div> | |||
==See Also== | ==See Also== | ||
| Line 25: | Line 27: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Human]] | ||
[[Category: Arrigoni, C]] | [[Category: Arrigoni, C]] | ||
[[Category: Bertinetti, D]] | [[Category: Bertinetti, D]] | ||