2wmr: Difference between revisions
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==CRYSTAL STRUCTURE OF CHECKPOINT KINASE 1 (CHK1) IN COMPLEX WITH INHIBITORS== | ==CRYSTAL STRUCTURE OF CHECKPOINT KINASE 1 (CHK1) IN COMPLEX WITH INHIBITORS== | ||
<StructureSection load='2wmr' size='340' side='right' caption='[[2wmr]], [[Resolution|resolution]] 2.43Å' scene=''> | <StructureSection load='2wmr' size='340' side='right' caption='[[2wmr]], [[Resolution|resolution]] 2.43Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2wmr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2wmr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WMR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WMR FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZYR:5,6,7,8-TETRAHYDRO[1]BENZOTHIENO[2,3-D]PYRIMIDIN-4(3H)-ONE'>ZYR</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZYR:5,6,7,8-TETRAHYDRO[1]BENZOTHIENO[2,3-D]PYRIMIDIN-4(3H)-ONE'>ZYR</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2cgx|2cgx]], [[2bro|2bro]], [[2c3j|2c3j]], [[2brb|2brb]], [[2brh|2brh]], [[2cgv|2cgv]], [[1nvr|1nvr]], [[2c3k|2c3k]], [[2cgw|2cgw]], [[1zlt|1zlt]], [[2brn|2brn]], [[2ayp|2ayp]], [[1zys|1zys]], [[2cgu|2cgu]], [[2br1|2br1]], [[1ia8|1ia8]], [[2brg|2brg]], [[1nvs|1nvs]], [[1nvq|1nvq]], [[2brm|2brm]], [[2c3l|2c3l]], [[2wmt|2wmt]], [[2wmx|2wmx]], [[2wmq|2wmq]], [[2wmv|2wmv]], [[2wms|2wms]], [[2wmw|2wmw]], [[2wmu|2wmu]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2cgx|2cgx]], [[2bro|2bro]], [[2c3j|2c3j]], [[2brb|2brb]], [[2brh|2brh]], [[2cgv|2cgv]], [[1nvr|1nvr]], [[2c3k|2c3k]], [[2cgw|2cgw]], [[1zlt|1zlt]], [[2brn|2brn]], [[2ayp|2ayp]], [[1zys|1zys]], [[2cgu|2cgu]], [[2br1|2br1]], [[1ia8|1ia8]], [[2brg|2brg]], [[1nvs|1nvs]], [[1nvq|1nvq]], [[2brm|2brm]], [[2c3l|2c3l]], [[2wmt|2wmt]], [[2wmx|2wmx]], [[2wmq|2wmq]], [[2wmv|2wmv]], [[2wms|2wms]], [[2wmw|2wmw]], [[2wmu|2wmu]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wmr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wmr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wmr RCSB], [http://www.ebi.ac.uk/pdbsum/2wmr PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wmr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wmr OCA], [http://pdbe.org/2wmr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wmr RCSB], [http://www.ebi.ac.uk/pdbsum/2wmr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wmr ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
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<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wmr ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 2wmr" style="background-color:#fffaf0;"></div> | |||
==See Also== | ==See Also== | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Human]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
[[Category: Aherne, G W]] | [[Category: Aherne, G W]] | ||