3isn: Difference between revisions
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==Crystal structure of HIV-1 RT bound to A 6-vinylpyrimidine inhibitor== | ==Crystal structure of HIV-1 RT bound to A 6-vinylpyrimidine inhibitor== | ||
<StructureSection load='3isn' size='340' side='right' caption='[[3isn]], [[Resolution|resolution]] 2.50Å' scene=''> | <StructureSection load='3isn' size='340' side='right' caption='[[3isn]], [[Resolution|resolution]] 2.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3isn]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[3isn]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Hiv-1 Hiv-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ISN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ISN FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDM:6-ETHENYL-N,N-DIMETHYL-2-(METHYLSULFONYL)PYRIMIDIN-4-AMINE'>EDM</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDM:6-ETHENYL-N,N-DIMETHYL-2-(METHYLSULFONYL)PYRIMIDIN-4-AMINE'>EDM</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3ith|3ith]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3ith|3ith]]</td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gag-pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id= | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gag-pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11678 HIV-1])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3isn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3isn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3isn RCSB], [http://www.ebi.ac.uk/pdbsum/3isn PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3isn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3isn OCA], [http://pdbe.org/3isn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3isn RCSB], [http://www.ebi.ac.uk/pdbsum/3isn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3isn ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
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<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3isn ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Hiv-1]] | ||
[[Category: Bec, G]] | [[Category: Bec, G]] | ||
[[Category: Botta, M]] | [[Category: Botta, M]] | ||
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[[Category: Freisz, S]] | [[Category: Freisz, S]] | ||
[[Category: Radi, M]] | [[Category: Radi, M]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: Inhibitor]] | [[Category: Inhibitor]] | ||
[[Category: Rt]] | [[Category: Rt]] | ||
[[Category: Transferase]] | [[Category: Transferase]] |