4tqb: Difference between revisions

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==The co-complex structure of the translation initiation factor eIF4E with the inhibitor 4EGI-1 reveals an allosteric mechanism for dissociating eIF4G==
==The co-complex structure of the translation initiation factor eIF4E with the inhibitor 4EGI-1 reveals an allosteric mechanism for dissociating eIF4G==
<StructureSection load='4tqb' size='340' side='right' caption='[[4tqb]], [[Resolution|resolution]] 1.59&Aring;' scene=''>
<StructureSection load='4tqb' size='340' side='right' caption='[[4tqb]], [[Resolution|resolution]] 1.59&Aring;' scene=''>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=34K:(2E)-2-{2-[4-(4-BROMOPHENYL)-1,3-THIAZOL-2-YL]HYDRAZINYLIDENE}-3-(2-NITROPHENYL)PROPANOIC+ACID'>34K</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=MGT:7N-METHYL-8-HYDROGUANOSINE-5-TRIPHOSPHATE'>MGT</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=34K:(2E)-2-{2-[4-(4-BROMOPHENYL)-1,3-THIAZOL-2-YL]HYDRAZINYLIDENE}-3-(2-NITROPHENYL)PROPANOIC+ACID'>34K</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=MGT:7N-METHYL-8-HYDROGUANOSINE-5-TRIPHOSPHATE'>MGT</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4tpw|4tpw]], [[4tqc|4tqc]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4tpw|4tpw]], [[4tqc|4tqc]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4tqb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tqb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4tqb RCSB], [http://www.ebi.ac.uk/pdbsum/4tqb PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4tqb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tqb OCA], [http://pdbe.org/4tqb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4tqb RCSB], [http://www.ebi.ac.uk/pdbsum/4tqb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4tqb ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4tqb" style="background-color:#fffaf0;"></div>
==See Also==
*[[Eukaryotic initiation factor|Eukaryotic initiation factor]]
== References ==
== References ==
<references/>
<references/>

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