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==Crystal structure of Staphylococcal nuclease variant Delta+PHS V99D at cryogenic temperature== | ==Crystal structure of Staphylococcal nuclease variant Delta+PHS V99D at cryogenic temperature== | ||
<StructureSection load='4eqo' size='340' side='right' caption='[[4eqo]], [[Resolution|resolution]] 1.70Å' scene=''> | <StructureSection load='4eqo' size='340' side='right' caption='[[4eqo]], [[Resolution|resolution]] 1.70Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4eqo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[4eqo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus aureus" (rosenbach 1884) zopf 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EQO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4EQO FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=THP:THYMIDINE-3,5-DIPHOSPHATE'>THP</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=THP:THYMIDINE-3,5-DIPHOSPHATE'>THP</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3bdc|3bdc]], [[3tp7|3tp7]], [[4eqn|4eqn]], [[4eqp|4eqp]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3bdc|3bdc]], [[3tp7|3tp7]], [[4eqn|4eqn]], [[4eqp|4eqp]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Micrococcal_nuclease Micrococcal nuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.31.1 3.1.31.1] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Micrococcal_nuclease Micrococcal nuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.31.1 3.1.31.1] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4eqo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eqo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4eqo RCSB], [http://www.ebi.ac.uk/pdbsum/4eqo PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4eqo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eqo OCA], [http://pdbe.org/4eqo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4eqo RCSB], [http://www.ebi.ac.uk/pdbsum/4eqo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4eqo ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Micrococcal nuclease]] | [[Category: Micrococcal nuclease]] | ||
[[Category: E., B Garcia-Moreno]] | [[Category: E., B Garcia-Moreno]] | ||
[[Category: Heroux, A]] | [[Category: Heroux, A]] |
Revision as of 16:28, 5 August 2016
Crystal structure of Staphylococcal nuclease variant Delta+PHS V99D at cryogenic temperatureCrystal structure of Staphylococcal nuclease variant Delta+PHS V99D at cryogenic temperature
Structural highlights
Function[NUC_STAAU] Enzyme that catalyzes the hydrolysis of both DNA and RNA at the 5' position of the phosphodiester bond. See Also |
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