3vml: Difference between revisions

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==Chimera 3-isopropylmalate dehydrogenase between Shewanella oneidensis MR-1 (O) and Shewanella benthica DB21 MT-2 (M) from N-terminal: 20% O middle 70% M residual 10% O==
==Chimera 3-isopropylmalate dehydrogenase between Shewanella oneidensis MR-1 (O) and Shewanella benthica DB21 MT-2 (M) from N-terminal: 20% O middle 70% M residual 10% O==
<StructureSection load='3vml' size='340' side='right' caption='[[3vml]], [[Resolution|resolution]] 1.56&Aring;' scene=''>
<StructureSection load='3vml' size='340' side='right' caption='[[3vml]], [[Resolution|resolution]] 1.56&Aring;' scene=''>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">leuB, SO_4235 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=43661 ATCC 43992])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">leuB, SO_4235 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=43661 ATCC 43992])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-isopropylmalate_dehydrogenase 3-isopropylmalate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.85 1.1.1.85] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-isopropylmalate_dehydrogenase 3-isopropylmalate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.85 1.1.1.85] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vml FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vml OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3vml RCSB], [http://www.ebi.ac.uk/pdbsum/3vml PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vml FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vml OCA], [http://pdbe.org/3vml PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3vml RCSB], [http://www.ebi.ac.uk/pdbsum/3vml PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3vml ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==

Revision as of 06:21, 5 August 2016

Chimera 3-isopropylmalate dehydrogenase between Shewanella oneidensis MR-1 (O) and Shewanella benthica DB21 MT-2 (M) from N-terminal: 20% O middle 70% M residual 10% OChimera 3-isopropylmalate dehydrogenase between Shewanella oneidensis MR-1 (O) and Shewanella benthica DB21 MT-2 (M) from N-terminal: 20% O middle 70% M residual 10% O

Structural highlights

3vml is a 1 chain structure with sequence from Atcc 43992. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, ,
Gene:leuB, SO_4235 (ATCC 43992)
Activity:3-isopropylmalate dehydrogenase, with EC number 1.1.1.85
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[LEU3_SHEON] Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.

See Also

3vml, resolution 1.56Å

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OCA