4uct: Difference between revisions

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-'''Unreleased structure'''
+==Fragment bound to H.influenza NAD dependent DNA ligase==
+<StructureSection load='4uct' size='340' side='right' caption='[[4uct]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
-The entry 4uct is ON HOLD  until Paper Publication
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4uct]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UCT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UCT FirstGlance]. <br>
-Authors: Hale, M., Brassington, C., Carcanague, D., Embrey, K., Eyermann, C.J., Giacobbe, R.A., Gingipali, L., Gowravaram, M., Harang, J., Howard, T., Ioannidis, G., Jahic, H., Kutschke, A., Laganas, V.A., Loch, J., Miller, M.D., Murphy-Benenato, K.E., Oguto, H., Otterbein, L., Patel, S.J., Shapiro, A.B., Boriack-Sjodin, P.A.
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5U1:2-AMINO-6-METHYL-5-(PROPAN-2-YLOXY)-3H-[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-8-IUM'>5U1</scene>, <scene name='pdbligand=IWH:1-(2,4-DIMETHYLBENZYL)-6-OXO-1,6-DIHYDROPYRIDINE-3-CARBOXAMIDE'>IWH</scene></td></tr>
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4uco|4uco]], [[4ucr|4ucr]], [[4ucs|4ucs]], [[4ucu|4ucu]], [[4ucv|4ucv]]</td></tr>
-Description: Fragment bound to H.influenza NAD dependent DNA ligase
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_ligase_(NAD(+)) DNA ligase (NAD(+))], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.5.1.2 6.5.1.2] </span></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uct FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uct OCA], [http://pdbe.org/4uct PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4uct RCSB], [http://www.ebi.ac.uk/pdbsum/4uct PDBsum]</span></td></tr>
-[[Category: Loch, J]]
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/DNLJ_HAEIN DNLJ_HAEIN]] DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity).
+__TOC__
+</StructureSection>
+[[Category: Boriack-Sjodin, P A]]
+[[Category: Brassington, C]]
+[[Category: Carcanague, D]]
 [[Category: Embrey, K]]
-[[Category: Miller, M.D]]
+[[Category: Eyermann, C J]]
-[[Category: Boriack-Sjodin, P.A]]
+[[Category: Giacobbe, R A]]
-[[Category: Eyermann, C.J]]
+[[Category: Gingipali, L]]
 [[Category: Gowravaram, M]]
 [[Category: Hale, M]]
-[[Category: Otterbein, L]]
+[[Category: Harang, J]]
 [[Category: Howard, T]]
-[[Category: Shapiro, A.B]]
+[[Category: Ioannidis, G]]
-[[Category: Gingipali, L]]
-[[Category: Laganas, V.A]]
 [[Category: Jahic, H]]
-[[Category: Murphy-Benenato, K.E]]
 [[Category: Kutschke, A]]
-[[Category: Brassington, C]]
+[[Category: Laganas, V A]]
-[[Category: Carcanague, D]]
+[[Category: Loch, J]]
-[[Category: Patel, S.J]]
+[[Category: Miller, M D]]
+[[Category: Murphy-Benenato, K E]]
 [[Category: Oguto, H]]
-[[Category: Ioannidis, G]]
+[[Category: Otterbein, L]]
-[[Category: Harang, J]]
+[[Category: Patel, S J]]
-[[Category: Giacobbe, R.A]]
+[[Category: Shapiro, A B]]
+[[Category: Ligase]]