3mlw: Difference between revisions

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==Crystal structure of anti-HIV-1 V3 Fab 1006-15D in complex with an MN V3 peptide==
==Crystal structure of anti-HIV-1 V3 Fab 1006-15D in complex with an MN V3 peptide==
<StructureSection load='3mlw' size='340' side='right' caption='[[3mlw]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='3mlw' size='340' side='right' caption='[[3mlw]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3mlw]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Hiv-1_m:b_mn Hiv-1 m:b_mn] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MLW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3MLW FirstGlance]. <br>
<table><tr><td colspan='2'>[[3mlw]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Hiv-1 Hiv-1] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MLW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3MLW FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3mlr|3mlr]], [[3mls|3mls]], [[3mlt|3mlt]], [[3mlu|3mlu]], [[3mlv|3mlv]], [[3mlx|3mlx]], [[3mly|3mly]], [[3mlz|3mlz]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3mlr|3mlr]], [[3mls|3mls]], [[3mlt|3mlt]], [[3mlu|3mlu]], [[3mlv|3mlv]], [[3mlx|3mlx]], [[3mly|3mly]], [[3mlz|3mlz]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mlw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mlw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3mlw RCSB], [http://www.ebi.ac.uk/pdbsum/3mlw PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mlw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mlw OCA], [http://pdbe.org/3mlw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3mlw RCSB], [http://www.ebi.ac.uk/pdbsum/3mlw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3mlw ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3mlw ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 3mlw" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
*[[Monoclonal Antibody|Monoclonal Antibody]]
*[[3D structures of monoclonal antibody|3D structures of monoclonal antibody]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Hiv-1 m:b_mn]]
[[Category: Hiv-1]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Kong, X P]]
[[Category: Kong, X P]]
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[[Category: Fab]]
[[Category: Fab]]
[[Category: Gp120]]
[[Category: Gp120]]
[[Category: Hiv-1]]
[[Category: Human monoclonal antibody]]
[[Category: Human monoclonal antibody]]
[[Category: Immune system]]
[[Category: Immune system]]
[[Category: Third variable loop]]
[[Category: Third variable loop]]

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