1acx: Difference between revisions

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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1acx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1acx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1acx RCSB], [http://www.ebi.ac.uk/pdbsum/1acx PDBsum]</span></td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1acx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1acx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1acx RCSB], [http://www.ebi.ac.uk/pdbsum/1acx PDBsum]</span></td></tr>
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== Function ==
[[http://www.uniprot.org/uniprot/ATXA_STRGL ATXA_STRGL]] Binds non-covalently to a chromophore which is the cytotoxic and mutagenic component of the antibiotic. The chromophore binds to DNA as a weak intercalator and causes single- and double-strand breaks.
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Revision as of 21:06, 24 December 2014

ACTINOXANTHIN STRUCTURE AT THE ATOMIC LEVEL (RUSSIAN)ACTINOXANTHIN STRUCTURE AT THE ATOMIC LEVEL (RUSSIAN)

Structural highlights

1acx is a 1 chain structure with sequence from Streptomyces globisporus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Resources:FirstGlance, OCA, RCSB, PDBsum

Function

[ATXA_STRGL] Binds non-covalently to a chromophore which is the cytotoxic and mutagenic component of the antibiotic. The chromophore binds to DNA as a weak intercalator and causes single- and double-strand breaks.

1acx, resolution 2.00Å

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OCA