3hps: Difference between revisions
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hps FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hps OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3hps RCSB], [http://www.ebi.ac.uk/pdbsum/3hps PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hps FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hps OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3hps RCSB], [http://www.ebi.ac.uk/pdbsum/3hps PDBsum]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/LEU1_MYCTU LEU1_MYCTU]] Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity). | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 07:12, 25 December 2014
Crystal structure of Mycobacterium tuberculosis LeuA complexed with ketoisocaproate (KIC)Crystal structure of Mycobacterium tuberculosis LeuA complexed with ketoisocaproate (KIC)
Structural highlights
Function[LEU1_MYCTU] Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity). Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. |
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