1ogu: Difference between revisions

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|PDB= 1ogu |SIZE=350|CAPTION= <scene name='initialview01'>1ogu</scene>, resolution 2.60&Aring;
|PDB= 1ogu |SIZE=350|CAPTION= <scene name='initialview01'>1ogu</scene>, resolution 2.60&Aring;
|SITE= <scene name='pdbsite=AC1:Sgm+Binding+Site+For+Chain+D'>AC1</scene>
|SITE= <scene name='pdbsite=AC1:Sgm+Binding+Site+For+Chain+D'>AC1</scene>
|LIGAND= <scene name='pdbligand=ST8:4-{[4-AMINO-6-(CYCLOHEXYLMETHOXY)-5-NITROSOPYRIMIDIN-2-YL]AMINO}BENZAMIDE'>ST8</scene> and <scene name='pdbligand=SGM:MONOTHIOGLYCEROL'>SGM</scene>
|LIGAND= <scene name='pdbligand=SGM:MONOTHIOGLYCEROL'>SGM</scene>, <scene name='pdbligand=ST8:4-{[4-AMINO-6-(CYCLOHEXYLMETHOXY)-5-NITROSOPYRIMIDIN-2-YL]AMINO}BENZAMIDE'>ST8</scene>, <scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Transferred_entry:_2.7.11.1 Transferred entry: 2.7.11.1], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.37 2.7.1.37]  
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span>
|GENE=  
|GENE=  
|DOMAIN=
|RELATEDENTRY=
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ogu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ogu OCA], [http://www.ebi.ac.uk/pdbsum/1ogu PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1ogu RCSB]</span>
}}
}}


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Structure-based design of 2-arylamino-4-cyclohexylmethyl-5-nitroso-6-aminopyrimidine inhibitors of cyclin-dependent kinases 1 and 2., Sayle KL, Bentley J, Boyle FT, Calvert AH, Cheng Y, Curtin NJ, Endicott JA, Golding BT, Hardcastle IR, Jewsbury P, Mesguiche V, Newell DR, Noble ME, Parsons RJ, Pratt DJ, Wang LZ, Griffin RJ, Bioorg Med Chem Lett. 2003 Sep 15;13(18):3079-82. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12941338 12941338]
Structure-based design of 2-arylamino-4-cyclohexylmethyl-5-nitroso-6-aminopyrimidine inhibitors of cyclin-dependent kinases 1 and 2., Sayle KL, Bentley J, Boyle FT, Calvert AH, Cheng Y, Curtin NJ, Endicott JA, Golding BT, Hardcastle IR, Jewsbury P, Mesguiche V, Newell DR, Noble ME, Parsons RJ, Pratt DJ, Wang LZ, Griffin RJ, Bioorg Med Chem Lett. 2003 Sep 15;13(18):3079-82. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12941338 12941338]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Protein complex]]
[[Category: Protein complex]]
[[Category: Transferred entry: 2 7.11 1]]
[[Category: Endicott, J A.]]
[[Category: Endicott, J A.]]
[[Category: Noble, M E.M.]]
[[Category: Noble, M E.M.]]
[[Category: Pratt, D J.]]
[[Category: Pratt, D J.]]
[[Category: SGM]]
[[Category: ST8]]
[[Category: atp-binding]]
[[Category: atp-binding]]
[[Category: cell cycle]]
[[Category: cell cycle]]
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[[Category: transferase]]
[[Category: transferase]]


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