1ny7: Difference between revisions
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|ACTIVITY= | |ACTIVITY= | ||
|GENE= | |GENE= | ||
|DOMAIN= | |||
|RELATEDENTRY=[[1bmv|1BMV]] | |||
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ny7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ny7 OCA], [http://www.ebi.ac.uk/pdbsum/1ny7 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1ny7 RCSB]</span> | |||
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[[Category: Usha, R.]] | [[Category: Usha, R.]] | ||
[[Category: comovirus]] | [[Category: comovirus]] | ||
[[Category: icosahedral virus]] | [[Category: icosahedral virus]] | ||
[[Category: viral coat protein]] | [[Category: viral coat protein,cowpea mosaic virus (cpmv)]] | ||
[[Category: virus]] | [[Category: virus]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 22:37:10 2008'' | ||
Revision as of 22:37, 30 March 2008
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| , resolution 3.00Å | |||||||
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| Related: | 1BMV
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| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
COWPEA MOSAIC VIRUS (CPMV)
OverviewOverview
Comoviruses are a group of plant viruses in the picornavirus superfamily. The type member of comoviruses, cowpea mosaic virus (CPMV), was crystallized in the cubic space group I23, a = 317 A and the hexagonal space group P6(1)22, a = 451 A, c = 1038 A. Structures of three closely similar nucleoprotein particles were determined in the cubic form. The roughly 300-A capsid was similar to the picornavirus capsid displaying a pseudo T = 3 (P = 3) surface lattice. The three beta-sandwich domains adopt two orientations, one with the long axis radial and the other two with the long axes tangential in reference to the capsid sphere. T = 3 viruses display one or the other of these two orientations. The CPMV capsid was permeable to cesium ions, leading to a disturbance of the beta-annulus inside a channel-like structure, suggesting an ion channel. The hexagonal crystal form diffracted X rays to 3 A resolution, despite the large unit cell. The large ( approximately 200 A) solvent channels in the lattice allow exchange of CPMV cognate Fab fragments. As an initial step in the structure determination of the CPMV/Fab complex, the P6(1)22 crystal structure was solved by molecular replacement with the CPMV model determined in the cubic cell.
About this StructureAbout this Structure
1NY7 is a Protein complex structure of sequences from Cowpea mosaic virus. Full crystallographic information is available from OCA.
ReferenceReference
The refined crystal structure of cowpea mosaic virus at 2.8 A resolution., Lin T, Chen Z, Usha R, Stauffacher CV, Dai JB, Schmidt T, Johnson JE, Virology. 1999 Dec 5;265(1):20-34. PMID:10603314
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