3am7: Difference between revisions
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3am7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3am7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3am7 RCSB], [http://www.ebi.ac.uk/pdbsum/3am7 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3am7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3am7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3am7 RCSB], [http://www.ebi.ac.uk/pdbsum/3am7 PDBsum]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/IF4E_HUMAN IF4E_HUMAN]] Its translation stimulation activity is repressed by binding to the complex CYFIP1-FMR1 (By similarity). Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap.<ref>PMID:16271312</ref> | |||
==See Also== | ==See Also== | ||
*[[Eukaryotic initiation factor|Eukaryotic initiation factor]] | *[[Eukaryotic initiation factor|Eukaryotic initiation factor]] | ||
== References == | |||
<references/> | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Fukuyo, A | [[Category: Fukuyo, A]] | ||
[[Category: In, Y | [[Category: In, Y]] | ||
[[Category: Ishida, T | [[Category: Ishida, T]] | ||
[[Category: Tomoo, K | [[Category: Tomoo, K]] | ||
[[Category: Cap]] | [[Category: Cap]] | ||
[[Category: Protein-protein complex]] | [[Category: Protein-protein complex]] | ||
[[Category: Translation]] | [[Category: Translation]] | ||
[[Category: Translation-protein binding complex]] | [[Category: Translation-protein binding complex]] | ||