2q53: Difference between revisions
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2q53 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2q53 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2q53 RCSB], [http://www.ebi.ac.uk/pdbsum/2q53 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2q53 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2q53 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2q53 RCSB], [http://www.ebi.ac.uk/pdbsum/2q53 PDBsum]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/CG024_HUMAN CG024_HUMAN]] Catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides and may play a significant role in glutathione homeostasis. Induces release of cytochrome c from mitochondria with resultant induction of apoptosis.<ref>PMID:16765912</ref> <ref>PMID:18515354</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
== References == | |||
<references/> | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Structural genomic]] | ||
[[Category: Kondrashov, D A | [[Category: Kondrashov, D A]] | ||
[[Category: Levin, E J | [[Category: Levin, E J]] | ||
[[Category: Phillips, G N | [[Category: Phillips, G N]] | ||
[[Category: Wesenberg, G E | [[Category: Wesenberg, G E]] | ||
[[Category: Cesg]] | [[Category: Cesg]] | ||
[[Category: Ensemble refinement]] | [[Category: Ensemble refinement]] | ||
[[Category: Protein structure initiative | [[Category: PSI, Protein structure initiative]] | ||
[[Category: Refinement methodology development]] | [[Category: Refinement methodology development]] | ||
[[Category: Unknown function]] | [[Category: Unknown function]] | ||
Revision as of 23:35, 25 December 2014
Ensemble refinement of the crystal structure of uncharacterized protein loc79017 from Homo sapiensEnsemble refinement of the crystal structure of uncharacterized protein loc79017 from Homo sapiens
Structural highlights
Function[CG024_HUMAN] Catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides and may play a significant role in glutathione homeostasis. Induces release of cytochrome c from mitochondria with resultant induction of apoptosis.[1] [2] Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. References
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