217d: Difference between revisions
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Chen, X | [[Category: Chen, X]] | ||
[[Category: Ramakrishnan, B | [[Category: Ramakrishnan, B]] | ||
[[Category: Sundaralingam, M | [[Category: Sundaralingam, M]] | ||
[[Category: B-dna/rna]] | [[Category: B-dna/rna]] | ||
[[Category: Complexed with drug]] | [[Category: Complexed with drug]] | ||
Revision as of 21:20, 15 January 2015
CRYSTAL STRUCTURES OF THE B-FORM DNA-RNA CHIMER (5'-D(*IP*)-R(*CP*)-D(*IP*)-R(*CP*)-D(*IP*CP*IP*C)-3') COMPLEXED WITH DISTAMYCINCRYSTAL STRUCTURES OF THE B-FORM DNA-RNA CHIMER (5'-D(*IP*)-R(*CP*)-D(*IP*)-R(*CP*)-D(*IP*CP*IP*C)-3') COMPLEXED WITH DISTAMYCIN
Structural highlights
Publication Abstract from PubMedTwo DNA-RNA chimers, complexed with DNA minor groove binding drugs, have been observed to adopt the B-form conformation for the first time. Thus, the RNA duplex may assume the B-DNA conformation when interacting with drugs, peptides or proteins. Crystal structures of B-form DNA-RNA chimers complexed with distamycin.,Chen X, Ramakrishnan B, Sundaralingam M Nat Struct Biol. 1995 Sep;2(9):733-5. PMID:7552741[1] From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. References |
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