2he4: Difference between revisions
No edit summary |
No edit summary |
||
| Line 3: | Line 3: | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2he4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HE4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HE4 FirstGlance]. <br> | <table><tr><td colspan='2'>[[2he4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HE4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HE4 FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>< | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SLC9A3R2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SLC9A3R2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2he4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2he4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2he4 RCSB], [http://www.ebi.ac.uk/pdbsum/2he4 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2he4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2he4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2he4 RCSB], [http://www.ebi.ac.uk/pdbsum/2he4 PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/NHRF2_HUMAN NHRF2_HUMAN]] Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. May also act as scaffold protein in the nucleus.<ref>PMID:9096337</ref> <ref>PMID:10455146</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 30: | Line 32: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Arrowsmith, C | [[Category: Arrowsmith, C]] | ||
[[Category: Berridge, G | [[Category: Berridge, G]] | ||
[[Category: Bunkoczi, G | [[Category: Bunkoczi, G]] | ||
[[Category: Colebrook, S | [[Category: Colebrook, S]] | ||
[[Category: Doyle, D A | [[Category: Doyle, D A]] | ||
[[Category: Edwards, A | [[Category: Edwards, A]] | ||
[[Category: Elkins, J M | [[Category: Elkins, J M]] | ||
[[Category: Gileadi, C | [[Category: Gileadi, C]] | ||
[[Category: Gileady, O | [[Category: Gileady, O]] | ||
[[Category: Gorrec, F | [[Category: Gorrec, F]] | ||
[[Category: Pantic, N | [[Category: Pantic, N]] | ||
[[Category: Papagrigoriou, E | [[Category: Papagrigoriou, E]] | ||
[[Category: | [[Category: Structural genomic]] | ||
[[Category: Salah, E | [[Category: Salah, E]] | ||
[[Category: Savitsky, P | [[Category: Savitsky, P]] | ||
[[Category: Sundstrom, M | [[Category: Sundstrom, M]] | ||
[[Category: Weigelt, J | [[Category: Weigelt, J]] | ||
[[Category: Phosphorylation]] | [[Category: Phosphorylation]] | ||
[[Category: Sgc]] | [[Category: Sgc]] | ||
[[Category: Unknown function]] | [[Category: Unknown function]] | ||