2azp: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
No edit summary
No edit summary
Line 3: Line 3:
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2azp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AZP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2AZP FirstGlance]. <br>
<table><tr><td colspan='2'>[[2azp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AZP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2AZP FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2azp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2azp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2azp RCSB], [http://www.ebi.ac.uk/pdbsum/2azp PDBsum], [http://www.topsan.org/Proteins/MCSG/2azp TOPSAN]</span></td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2azp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2azp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2azp RCSB], [http://www.ebi.ac.uk/pdbsum/2azp PDBsum], [http://www.topsan.org/Proteins/MCSG/2azp TOPSAN]</span></td></tr>
<table>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/HYPRE_PSEAE HYPRE_PSEAE]] Allows intracellular utilization of 4-hydroxyproline, one of the major constituents of host collagen, by converting 4-hydroxy-L-proline to 4-hydroxy-D-proline, which can be further metabolized by intracellular 4-hydroxy-D-proline oxidases. Strong B-cell mitogen. Plays an important role in the regulation of intra- and extracellular amino acid pools, allowing the bacterium to profit from host precursors and enzymatic pathways.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 18: Line 20:
</StructureSection>
</StructureSection>
[[Category: Pseudomonas aeruginosa]]
[[Category: Pseudomonas aeruginosa]]
[[Category: Edwards, A.]]
[[Category: Edwards, A]]
[[Category: Gorodichtchenskaia, E.]]
[[Category: Gorodichtchenskaia, E]]
[[Category: Joachimiak, A.]]
[[Category: Joachimiak, A]]
[[Category: Liu, Y.]]
[[Category: Liu, Y]]
[[Category: MCSG, Midwest Center for Structural Genomics.]]
[[Category: Structural genomic]]
[[Category: Pai, E F.]]
[[Category: Pai, E F]]
[[Category: Savchenko, A.]]
[[Category: Savchenko, A]]
[[Category: Skarina, T.]]
[[Category: Skarina, T]]
[[Category: Yang, C.]]
[[Category: Yang, C]]
[[Category: Apc5861]]
[[Category: Apc5861]]
[[Category: Mcsg]]
[[Category: Mcsg]]
[[Category: Midwest center for structural genomic]]
[[Category: Pa1268]]
[[Category: Pa1268]]
[[Category: Protein structure initiative]]
[[Category: PSI, Protein structure initiative]]
[[Category: Psi]]
[[Category: Structural genomic]]
[[Category: Sulfur sad]]
[[Category: Sulfur sad]]
[[Category: Unknown function]]
[[Category: Unknown function]]

Revision as of 21:50, 25 December 2014

Crystal Structure of PA1268 Solved by Sulfur SADCrystal Structure of PA1268 Solved by Sulfur SAD

Structural highlights

2azp is a 1 chain structure with sequence from Pseudomonas aeruginosa. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Resources:FirstGlance, OCA, RCSB, PDBsum, TOPSAN

Function

[HYPRE_PSEAE] Allows intracellular utilization of 4-hydroxyproline, one of the major constituents of host collagen, by converting 4-hydroxy-L-proline to 4-hydroxy-D-proline, which can be further metabolized by intracellular 4-hydroxy-D-proline oxidases. Strong B-cell mitogen. Plays an important role in the regulation of intra- and extracellular amino acid pools, allowing the bacterium to profit from host precursors and enzymatic pathways.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

2azp, resolution 2.13Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA