2cz0: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2cz0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhodococcus_erythropolis Rhodococcus erythropolis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CZ0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CZ0 FirstGlance]. <br> | <table><tr><td colspan='2'>[[2cz0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhodococcus_erythropolis Rhodococcus erythropolis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CZ0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CZ0 FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BUA:BUTANOIC+ACID'>BUA</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>< | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BUA:BUTANOIC+ACID'>BUA</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene></td></tr> | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2cyz|2cyz]], [[2cz1|2cz1]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2cyz|2cyz]], [[2cz1|2cz1]]</td></tr> | ||
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Nitrile_hydratase Nitrile hydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.84 4.2.1.84] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Nitrile_hydratase Nitrile hydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.84 4.2.1.84] </span></td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cz0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cz0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2cz0 RCSB], [http://www.ebi.ac.uk/pdbsum/2cz0 PDBsum], [http://www.topsan.org/Proteins/RSGI/2cz0 TOPSAN]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cz0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cz0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2cz0 RCSB], [http://www.ebi.ac.uk/pdbsum/2cz0 PDBsum], [http://www.topsan.org/Proteins/RSGI/2cz0 TOPSAN]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/NHAA_RHOER NHAA_RHOER]] NHase catalyzes the hydration of various nitrile compounds to the corresponding amides. Industrial production of acrylamide is now being developed using some of the enzymes of this class. [[http://www.uniprot.org/uniprot/NHAB_RHOER NHAB_RHOER]] NHase catalyzes the hydration of various nitrile compounds to the corresponding amides. | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Nitrile hydratase]] | [[Category: Nitrile hydratase]] | ||
[[Category: Rhodococcus erythropolis]] | [[Category: Rhodococcus erythropolis]] | ||
[[Category: Endo, I | [[Category: Endo, I]] | ||
[[Category: Hashimoto, K | [[Category: Hashimoto, K]] | ||
[[Category: Kamiya, N | [[Category: Kamiya, N]] | ||
[[Category: Kawano, Y | [[Category: Kawano, Y]] | ||
[[Category: Nakayama, H | [[Category: Nakayama, H]] | ||
[[Category: Odaka, M | [[Category: Odaka, M]] | ||
[[Category: | [[Category: Structural genomic]] | ||
[[Category: Takio, K | [[Category: Takio, K]] | ||
[[Category: Cysteine-sulfenic acid]] | [[Category: Cysteine-sulfenic acid]] | ||
[[Category: Cysteine-sulfinic acid]] | [[Category: Cysteine-sulfinic acid]] | ||
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[[Category: Photo-reactive]] | [[Category: Photo-reactive]] | ||
[[Category: Post-translational modification]] | [[Category: Post-translational modification]] | ||
[[Category: Rsgi]] | [[Category: Rsgi]] | ||