1z8g: Difference between revisions

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1z8g]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z8G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Z8G FirstGlance]. <br>
<table><tr><td colspan='2'>[[1z8g]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z8G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Z8G FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=0QE:CHLOROMETHANE'>0QE</scene>, <scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=AR7:AMINO{[(4S)-4-AMINO-5,5-DIHYDROXYPENTYL]AMINO}METHANIMINIUM'>AR7</scene></td></tr>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=0QE:CHLOROMETHANE'>0QE</scene>, <scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=AR7:AMINO{[(4S)-4-AMINO-5,5-DIHYDROXYPENTYL]AMINO}METHANIMINIUM'>AR7</scene></td></tr>
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HPN, TMPRSS1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HPN, TMPRSS1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1z8g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z8g OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1z8g RCSB], [http://www.ebi.ac.uk/pdbsum/1z8g PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1z8g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z8g OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1z8g RCSB], [http://www.ebi.ac.uk/pdbsum/1z8g PDBsum]</span></td></tr>
<table>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/HEPS_HUMAN HEPS_HUMAN]] Plays an essential role in cell growth and maintenance of cell morphology. May mediate the activating cleavage of HGF and MST1/HGFL.<ref>PMID:21875933</ref> <ref>PMID:15839837</ref> 
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Aaron, W.]]
[[Category: Aaron, W]]
[[Category: Austin, R J.]]
[[Category: Austin, R J]]
[[Category: Bhatt, A S.]]
[[Category: Bhatt, A S]]
[[Category: Cao, P.]]
[[Category: Cao, P]]
[[Category: Choe, Y.]]
[[Category: Choe, Y]]
[[Category: Craik, C S.]]
[[Category: Craik, C S]]
[[Category: Cutler, G.]]
[[Category: Cutler, G]]
[[Category: Gabriele, T.]]
[[Category: Gabriele, T]]
[[Category: Herter, S.]]
[[Category: Herter, S]]
[[Category: Hoey, T.]]
[[Category: Hoey, T]]
[[Category: Meininger, D.]]
[[Category: Meininger, D]]
[[Category: Piper, D E.]]
[[Category: Piper, D E]]
[[Category: Walker, N.]]
[[Category: Walker, N]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Protease]]
[[Category: Protease]]
[[Category: Serine protease hepsin]]
[[Category: Serine protease hepsin]]

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