2wxg: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2wxg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WXG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WXG FirstGlance]. <br> | <table><tr><td colspan='2'>[[2wxg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WXG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WXG FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZZN:2-{[4-AMINO-3-(3-FLUORO-5-HYDROXYPHENYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-1-YL]METHYL}-5-METHYL-3-(2-METHYLPHENYL)QUINAZOLIN-4(3H)-ONE'>ZZN</scene>< | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZZN:2-{[4-AMINO-3-(3-FLUORO-5-HYDROXYPHENYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-1-YL]METHYL}-5-METHYL-3-(2-METHYLPHENYL)QUINAZOLIN-4(3H)-ONE'>ZZN</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2wxm|2wxm]], [[2wxh|2wxh]], [[2wxk|2wxk]], [[2wxl|2wxl]], [[2wxi|2wxi]], [[2wxp|2wxp]], [[2wxo|2wxo]], [[2wxf|2wxf]], [[2wxq|2wxq]], [[2wxn|2wxn]], [[2wxe|2wxe]], [[2wxj|2wxj]], [[2wxr|2wxr]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2wxm|2wxm]], [[2wxh|2wxh]], [[2wxk|2wxk]], [[2wxl|2wxl]], [[2wxi|2wxi]], [[2wxp|2wxp]], [[2wxo|2wxo]], [[2wxf|2wxf]], [[2wxq|2wxq]], [[2wxn|2wxn]], [[2wxe|2wxe]], [[2wxj|2wxj]], [[2wxr|2wxr]]</td></tr> | ||
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphatidylinositol-4,5-bisphosphate_3-kinase Phosphatidylinositol-4,5-bisphosphate 3-kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.153 2.7.1.153] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphatidylinositol-4,5-bisphosphate_3-kinase Phosphatidylinositol-4,5-bisphosphate 3-kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.153 2.7.1.153] </span></td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wxg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wxg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wxg RCSB], [http://www.ebi.ac.uk/pdbsum/2wxg PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wxg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wxg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wxg RCSB], [http://www.ebi.ac.uk/pdbsum/2wxg PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
[[Category: Phosphatidylinositol-4,5-bisphosphate 3-kinase]] | [[Category: Phosphatidylinositol-4,5-bisphosphate 3-kinase]] | ||
[[Category: Berndt, A | [[Category: Berndt, A]] | ||
[[Category: Gaillard, P | [[Category: Gaillard, P]] | ||
[[Category: Gorrec, F | [[Category: Gorrec, F]] | ||
[[Category: Hon, W C | [[Category: Hon, W C]] | ||
[[Category: Houseman, B T | [[Category: Houseman, B T]] | ||
[[Category: Lee, D D | [[Category: Lee, D D]] | ||
[[Category: Liu, Y | [[Category: Liu, Y]] | ||
[[Category: Miller, S | [[Category: Miller, S]] | ||
[[Category: Pacold, J I | [[Category: Pacold, J I]] | ||
[[Category: Rommel, C | [[Category: Rommel, C]] | ||
[[Category: Ruckle, T | [[Category: Ruckle, T]] | ||
[[Category: Schwarz, M K | [[Category: Schwarz, M K]] | ||
[[Category: Shaw, J P | [[Category: Shaw, J P]] | ||
[[Category: Shokat, K M | [[Category: Shokat, K M]] | ||
[[Category: Williams, O | [[Category: Williams, O]] | ||
[[Category: Williams, R L | [[Category: Williams, R L]] | ||
[[Category: Cancer]] | [[Category: Cancer]] | ||
[[Category: Isoform-specific inhibitor]] | [[Category: Isoform-specific inhibitor]] | ||
[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||