2c0h: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2c0h]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mytilus_edulis Mytilus edulis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C0H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2C0H FirstGlance]. <br> | <table><tr><td colspan='2'>[[2c0h]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mytilus_edulis Mytilus edulis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C0H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2C0H FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>< | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mannan_endo-1,4-beta-mannosidase Mannan endo-1,4-beta-mannosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.78 3.2.1.78] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mannan_endo-1,4-beta-mannosidase Mannan endo-1,4-beta-mannosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.78 3.2.1.78] </span></td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2c0h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c0h OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2c0h RCSB], [http://www.ebi.ac.uk/pdbsum/2c0h PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2c0h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c0h OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2c0h RCSB], [http://www.ebi.ac.uk/pdbsum/2c0h PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/MANA_MYTED MANA_MYTED]] Hydrolyzes 1,4-beta linked polysaccharide backbones of mannans. Hydrolyzes mannohexaose (M6) preferentially to mannotriose (M4) and less preferentially to mannotetraose (M3), mannopentaose (M5), and mannobiose (M2); hydrolyzes M5 preferentially to M2, and M3, and less preferentially to mannotetraose M4; hydrolyzes M4 preferentially to M3, and less preferentially to mannose (M1), plus very little M2. Does not hydrolyze mannobiose or mannotriose. Does not hydrolyze xlyan, starch, cellulose or galactose.<ref>PMID:11895446</ref> <ref>PMID:11689251</ref> <ref>PMID:16487541</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Mannan endo-1,4-beta-mannosidase]] | [[Category: Mannan endo-1,4-beta-mannosidase]] | ||
[[Category: Mytilus edulis]] | [[Category: Mytilus edulis]] | ||
[[Category: Anderson, L | [[Category: Anderson, L]] | ||
[[Category: Janson, J C | [[Category: Janson, J C]] | ||
[[Category: Larsson, A M | [[Category: Larsson, A M]] | ||
[[Category: Munoz, I G | [[Category: Munoz, I G]] | ||
[[Category: Stahlberg, J | [[Category: Stahlberg, J]] | ||
[[Category: Stalbrand, H | [[Category: Stalbrand, H]] | ||
[[Category: Uson, I | [[Category: Uson, I]] | ||
[[Category: Xu, B | [[Category: Xu, B]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: Mytilus eduli]] | [[Category: Mytilus eduli]] | ||
[[Category: Tim alpha/beta barrel]] | [[Category: Tim alpha/beta barrel]] | ||