2gf0: Difference between revisions

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2gf0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GF0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GF0 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2gf0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GF0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GF0 FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene><br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DIRAS1, GBTS1, RIG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DIRAS1, GBTS1, RIG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gf0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gf0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2gf0 RCSB], [http://www.ebi.ac.uk/pdbsum/2gf0 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gf0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gf0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2gf0 RCSB], [http://www.ebi.ac.uk/pdbsum/2gf0 PDBsum]</span></td></tr>
<table>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/DIRA1_HUMAN DIRA1_HUMAN]] Displays low GTPase activity and exist predominantly in the GTP-bound form.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Arrowsmith, C.]]
[[Category: Arrowsmith, C]]
[[Category: Bray, J.]]
[[Category: Bray, J]]
[[Category: Delft, F von.]]
[[Category: Delft, F von]]
[[Category: Doyle, D.]]
[[Category: Doyle, D]]
[[Category: Edwards, A.]]
[[Category: Edwards, A]]
[[Category: Elkins, J.]]
[[Category: Elkins, J]]
[[Category: Fedorov, O.]]
[[Category: Fedorov, O]]
[[Category: Gileadi, O.]]
[[Category: Gileadi, O]]
[[Category: Niesen, F E.]]
[[Category: Niesen, F E]]
[[Category: Papagrigoriou, E.]]
[[Category: Papagrigoriou, E]]
[[Category: SGC, Structural Genomics Consortium.]]
[[Category: Structural genomic]]
[[Category: Salah, E.]]
[[Category: Salah, E]]
[[Category: Schoch, G.]]
[[Category: Schoch, G]]
[[Category: Sundstrom, M.]]
[[Category: Sundstrom, M]]
[[Category: Turnbull, A P.]]
[[Category: Turnbull, A P]]
[[Category: Weigelt, J.]]
[[Category: Weigelt, J]]
[[Category: Wen-Hwa, L.]]
[[Category: Wen-Hwa, L]]
[[Category: Yang, X.]]
[[Category: Yang, X]]
[[Category: Dira]]
[[Category: Dira]]
[[Category: Gdp/gtp binding]]
[[Category: Gdp/gtp binding]]
[[Category: Gtp hydrolysis]]
[[Category: Gtp hydrolysis]]
[[Category: Sgc]]
[[Category: Sgc]]
[[Category: Structural genomic]]
[[Category: Structural genomics consortium]]
[[Category: Transport protein]]
[[Category: Transport protein]]

Revision as of 15:40, 25 December 2014

The crystal structure of the human DiRas1 GTPase in the inactive GDP bound stateThe crystal structure of the human DiRas1 GTPase in the inactive GDP bound state

Structural highlights

2gf0 is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Gene:DIRAS1, GBTS1, RIG (Homo sapiens)
Resources:FirstGlance, OCA, RCSB, PDBsum

Function

[DIRA1_HUMAN] Displays low GTPase activity and exist predominantly in the GTP-bound form.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2gf0, resolution 1.90Å

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA